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Senior Scientist, In Vitro/Ex Vivo - Ophthalmology

Company: Novartis Group
Location: Cambridge
Posted on: August 5, 2022

Job Description:

Senior Scientist, In Vitro/Ex Vivo - OphthalmologyJob Description60 million! That is how many people are affected globally by glaucoma. This can lead to progressive damage to retinal ganglion cells and the optic nerve and may lead to blindness.

At Novartis, we are developing new therapies to treat glaucoma, the silent thief of sight, and prevent glaucoma disease progression by lowering eye pressure and by protecting retinal neurons.

We are looking for an experienced scientist to join our Ophthalmology Department to support the discovery and development of innovative glaucoma treatments.

What you'll be doing:

---Applying your training to discover novel biology in the field of neurodegeneration and neuroinflammation using in vitro, ex vivo, and in vivo systems.
---Contribute to experimental design, and independently perform experiments, troubleshoot issues, evaluate data, generate reports, suggest next steps, and present data at internal forums.
---Stay current on literature and technological advances and to collaborate with cross-functional teams on mechanisms of action studies, target discovery, and drug development.
---Assist in general laboratory maintenance.

EEO StatementThe Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.What you'll bring to the role:

---MS or BS in Biology, Immunology, Neurobiology, or related field with > 3 years of full time academic or industry laboratory experience. The level of the position will be commensurate with experience.
---Demonstrated proficiency in a broad range of techniques in molecular/ protein/ cell biology (such as qPCR, RNA/DNA preparation, CRISPR gene editing, Western blotting, cell transfection/transduction, AAV/Lenti-viral vectors, immunofluorescent staining, flow cytometry, fluorescent microscopy imaging, and ELISA).
---Hands-on experience in culturing primary cells or ESC/iPSC-derived cells.
---Highly motivated self-starter and problem-solver with a demonstrated ability to adapt quickly, work independently, and ability to thrive in a fast-paced collaborative research environment.
---Demonstrated strong communication skills, collaboration skills and attention to details.
---Training in ophthalmology, neuroscience, or immunology is a plus.
---Familiarity with tissue microdissection, explant culture, primary cell isolation from tissues, complex cell culture systems, and phenotypic assays is a plus.

Why consider Novartis?

769 million. That's how many lives our products touch. At Novartis, being there when and how it matters most for our patients and customers allows us to live our purpose and help bring maximum impact to health outcomes.

Furthering our commitment to transforming medicine for patients, Novartis is embarking on an ambitious and exciting journey to reinvent how we use technology, data and customer insights to better serve our consumer's needs and put them on a path to better health. This includes taking bold approaches that begin with a customer-centric mindset and harness the power of today's digital and data-driven healthcare revolution to continue to improve and extend even more people's lives.

--- Do you want to help people understand their disease and how to seek out the proper treatment for it?
--- Do you want to support patients in order to achieve the best possible outcomes?
--- Do you want to deliver a leading customer experience at all touchpoints?
--- Do you want to be at the forefront of leveraging today's technology advances to create tomorrow's healthcare innovations?

We believe the answers are found when curious, adventurous, and collaborative people like you are brought together in an inspiring environment. Where you're given opportunities to utilize the power of digital and data to individualize and maximize interactions with customers. Where you're empowered to not fear failure when taking smart risks. And most importantly, where you're surrounded by people who share your determination to tackle the world's toughest medical challenges.

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve.

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: If playback doesn't begin shortly, try restarting your device. Videos you watch may be added to the TV's watch history and influence TV recommendations. To avoid this, cancel and sign in to YouTube on your computer. Switch camera Share Include playlist An error occurred while retrieving sharing information. Please try again later.

Keywords: Novartis Group, Cambridge , Senior Scientist, In Vitro/Ex Vivo - Ophthalmology, Other , Cambridge, Massachusetts

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