Senior Director, US Medical Affairs - Head of Rheumatology

Company: Takeda
Location: Cambridge
Posted on: November 1, 2025

Job Description:

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: Join Takeda as the Senior Director, US Medical Affairs - Head of Rheumatology in Cambridge, MA. This is a critical role within the US Medical Affairs (USMA) organization that reports to the Vice President US Medical, Dermatology and Rheumatology. The role has responsibility for the zasocitinib Rheumatology programs/indications and is accountable for medical strategy, ensuring that TA and product-specific strategies are developed and executed in collaboration with the Medical Unit. You will serve as a? Subject Matter Expert (SME), representing the USMA on relevant internal committees and with external experts/committees. The role is accountable for overseeing data generation activities, including phase 4 clinical studies, providing coaching/mentorship to team managers, as appropriate. Further, the Senior Director will contribute to the medical unit insights, including ad boards, and communications with cross-functional partners. How you will contribute: Overarching Responsibilities: Strategic responsibility for zasocitinib rheumatology Phase 4 programs TA and/or product focus may evolve to support priorities of the organization (e.g. additional TA or product specific responsibilities may change based upon strategic direction of the organization). Oversee and/or delegate execution of medical strategies by the medical unit partner with the PM to track progress against strategic plans, including development communication of periodic reports. Develop US Product Medical Strategy: Co-develop/coordinate with the medical unit and provide medical input into the near-term and long-term strategic direction for assigned product/franchise. Accountable for development and ongoing updates to relevant product specific medical strategies, in partnership with medical unit, and in alignment with the commercial brand strategy and global product teams Collaborate with Value and Evidence Generation (VEG) team to develop evidence generation strategy. Develop long-term lifecycle management strategy tactics (HEOR etc.). Collaborate with PM (as applicable) to develop and maintain medical landscape and insights to inform strategy. Leverage advanced artificial intelligence tools and data analytics to inform, shape, and support medical strategies, foster innovation, improve efficiencies, and decision-making processes. Identify critical opportunities to leverage emerging AI technologies to improve rheumatology patient care and the broader healthcare landscape. Medical Expert: Serve as the in-house medical and scientific expert for therapies within the assigned TA and represent medical affairs at various internal and external meetings for zasocitinib rheumatology programs/indications. Insights Generation: Generate Insights – Develop and execute ad board strategies, which may be done in partnership with the PM (as applicable), and insights from field medical / additional sources. Understand and Communicate Insights: Synthesize summarized insights implications from relevant sources (e.g., ad boards, field medical) to medical unit and cross-functional stakeholders and update medical landscape medical strategy (as appropriate). External Engagement: Develop external KOL relationships and insights through Advisory Boards, professional associations/meetings and conferences etc.; manage global interactions with US KOLs. Partner with US Strategic Medical Alliances group on external partnership, as appropriate (e.g., external affairs/government affairs). Budget Management: Accountable for budget and ongoing budget management in partnership with the PM or delegates, and in concert with TA Head. Execution / Content Creation: Partner with the medical unit functional leads to ensure strategic alignment related to execution of the relevant franchise / product medical strategy and how it is pulled through into tactics (e.g. Grants, Medical Communications (e.g. SCP, ICP, Slide Decks), Publications, Research, Field Medical, Etc.). Support medical review of appropriate materials as part of medical and commercial review processes. Internal Engagement: Lead / coordinate with the medical unit, including attending regular meetings, and representing on the SLT Represent medical affairs (i.e., be the point of contact) on cross-functional / cross-division meetings (representation on global medical forums, commercial / product forums, etc.). Provide input into confidential new business development. Leadership Behaviors: Demonstrates strategic enterprise thinking finding innovative ways to serve patients, and build trust, reputation and business Creates the environment that inspires and enables people to move the organization forward Focuses on a few priorities and delivers superior results Elevates the capabilities of the organization for now and the future Demonstrated ability to communicate and influence up, down, cross-functionally with ability to influence internally, and externally Executive Presence & strategic storytelling Ability to oversee and delegate, and manage stakeholders Demonstrate strong partnerships and collaboration Minimum Requirements/Qualifications: Advanced Doctoral Degree (e.g., MD, DO, PhD, PharmD) 12 years of pharmaceutical industry experience; 7 years of relevant clinical practice, research, academic Experience with clinical research, publication activities, congress presentations, and public speaking. Dermatology and/or rheumatology experience Proficiency in evaluating, adopting, and embedding AI-powered solutions and platforms within medical affairs, enhancing both internal processes and/or external stakeholder engagement. Ability to leverage advanced artificial intelligence tools and data analytics to inform and guide medical strategies. Dedication to ongoing education in emerging AI technologies, trends, and their implications for the advancement of rheumatology patient care and the healthcare industry at large. Commitment to upholding the highest standards of data privacy, ethics, and regulatory compliance in the application of AI within medical affairs activities. Travel up to 30%, primarily domestic More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Cambridge, MA U.S. Base Salary Range: $228,900.00 - $359,700.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Cambridge, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Keywords: Takeda, Cambridge , Senior Director, US Medical Affairs - Head of Rheumatology, Science, Research & Development , Cambridge, Massachusetts