2023 Experiential Internship - Bioassay Development (California)

Company: AbbVie
Location: Cambridge
Posted on: March 20, 2023

Job Description:

ABOUT ABBVIEAbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.For more information about AbbVie, please visit us at--www.abbvie.com.Follow--@abbvie--on--Twitter,--Facebook,--Instagram,--YouTube,--and--LinkedIn.--BIOASSAY DEVELOPMENT INTERNSHIP OVERVIEWEnvision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie's Experiential Interns.The Bioassay Development Intern will support the Biologics Analytical Research and Development (Bio-ARD) team. The Bio-ARD team is responsible for all aspects of CMC analytical development required to advance new biologic candidates into clinical studies.In this lab-based role, you will work with a scientific mentor to investigate, develop, and optimize target-binding potency assays using laboratory methods such as Biolayer Interferometry, TR-FRET, and/or cell-based assays. The Intern will apply these methods to characterize novel protein therapeutics, including bispecifics, antibody drug conjugates (ADCs) and/or monoclonal antibodies to support development of new biologic drugs.KEY RESPONSIBILITIES INCLUDE:

• Develop, optimize, and apply binding potency methods for characterization of protein therapeutics
• Perform method robustness and accuracy studies
• Sample preparation and operation of instrumentation, including Octet BLI and Envision plate reader
• Design and execute experiments
• Analyze and interpret data
• Organize and document data in a lab notebook
• Present work and results in team/group meetingsMINIMUM QUALIFICATIONS
  • Currently enrolled in university, pursuing a Master's or PhD in Biology, Chemical Biology, Biochemistry, or other related field
  • Must be enrolled in university during the internship period
  • Knowledge and hands-on experience with common laboratory techniques (pipetting, sample dilution, aseptic cell-culture technique, and buffer preparation)
  • Strong written, verbal and oral communication skills
  • Hard-working, detail-oriented and demonstrated ability to quickly learn new skills
  • Collaborative team playerPREFERRED QUALIFICATIONS
    • Exposure to binding assays, cell-based assays, biotechnology, monoclonal antibodies
    • Experience in SPR, BLI and protein labeling
    • Excellent quantitative skills and prior experience with kinetic measurement (Kd, IC50, Kon/off) and/or analytical software (PRISM, Parallel Line Analysis, Softmax Pro)BENEFITS AND AMENITIES
      • Competitive pay
      • Travel, transportation and lodging support for eligible students
      • Break rooms stocked with complimentary coffee, tea, beverages, snacks, and cold breakfast items
      • Onsite caf-- and fitness centerEQUAL EMPLOYMENT OPPORTUNITYAt AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.Applicable to California Applicants Only
        • The below range is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. We may ultimately pay more or less than the posted range and this range is only applicable for jobs to be performed in California.This range may be modified in the future.
          • The salary range is (minimum: $51,750 to maximum: $101,250)
            • Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.

Keywords: AbbVie, Cambridge , 2023 Experiential Internship - Bioassay Development (California), Other , Cambridge, Massachusetts