Principal Scientist, LNP Process Development

Company: Intellia Therapeutics
Location: Cambridge
Posted on: March 19, 2023

Job Description:

Principal Scientist, LNP Process Development page is loaded Principal Scientist, LNP Process Development Apply locations Cambridge, MA time type Full time posted on Posted 30+ Days Ago job requisition id R821 Why Join Intellia? - Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just "treat" people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together. How you will Achieve More with Intellia:In this role, you will join the LNP Process Sciences group, where we develop lipid nanoparticle (LNP) formulations to deliver curative CRISPR gene editing therapeutics. This role is a leadership role: you will be responsible for overseeing the transition of new exciting therapies from idea into the development pipeline. This involves working with disease program teams as well as colleagues in delivery science as they discover new molecules for CRISPR delivery. Your role will involve understanding these new advancements and providing materials and early development to help push them forward as the next wave of curative therapies. You will be involved in helping to create and develop novel process development unit operations to help expand the Intellia process toolbox. You will also be responsible for managing and overseeing a small team of scientists to keep this work moving forward.About You:We are seeking a highly motivated Principal Scientist with strong leadership and communication skills. Our ideal candidate will have a PhD in Engineering, Chemistry or Pharmaceutical Sciences with 5-10 years of industry experience, or M.S. in Engineering, Chemistry or Pharmaceutical Sciences with 11-16 years of industry experience, or a Bachelor's Degree in Engineering, Chemistry or Pharmaceutical Sciences with 13-18 years of industry experience. If you describe yourself as a great team player who wants to help drive curative therapies to the clinic and beyond, we encourage you to apply! Other desired skills include:

• Experience designing, executing, and analyzing particle-based drug delivery systems
• Experience leading a team with fast paced work and high visibility deliverables
• Preferably has prior experience with LNP formulations with nucleic acids
• Preferably has prior experience working with a frozen or lyophilized particle-based drug product.
• Proficiency with a broad spectrum of analytical techniques applicable to nucleic acid drug delivery systems (i.e. particle size, fluorescent assays, HPLC/UPLC, etc).
• Demonstrates creativity and problem-solving skills
• Ability to work independently, as well as part of a team
• Organized, detail-oriented, and a self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills.Meet your future team:The LNP Process Sciences team are a group of highly skilled, energetic group of scientists and engineers who are excited about bringing potentially curative therapeutics to the world. Our team works across a wide range of disease areas, and the highly dynamic and collaborative nature of our work provides the opportunity to really see the full breadth of Intellia's cutting edge gene therapy technology. Your future hiring manager is the Director of LNP Process Sciences and has been with Intellia since Mar. 2017. He has worked on LNP processes for over 13 years and currently works for several programs and collaborates with colleagues across both Research and Development. Your future team helps drive technology from research all the way to the clinic and beyond. Apply today to join our team-we look forward to learning from you and working together!Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. About Us At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.

Keywords: Intellia Therapeutics, Cambridge , Principal Scientist, LNP Process Development, Other , Cambridge, Massachusetts