Head of Design and Informatics

Company: GlaxoSmithKline
Location: Cambridge
Posted on: March 18, 2023

Job Description:

Head of Oligo Platform Design and Informatics page is loaded Head of Oligo Platform Design and Informatics Apply locations USA - Massachusetts - Cambridge time type Full time posted on Posted Today job requisition id 365074 About the Role If you want to be part of a collaborative and focused team with a mission to build GSK's new therapeutic oligo platform, please apply! We're seeking an experienced Head of Oligo Design and Informatics to join the RNA therapeutic team within the Medicines Design organization. As the successful candidate, you will manage GSK's RNA therapeutic design strategy and its implementation on the discovery portfolio. The position will be responsible for building and leading the quantitative biology and data analytics for the therapeutics oligo team . You will be responsible for establishing the strategy, infrastructure, data capture, internal expertise and analytics necessary to realize GSK's future RNA therapeutic ambitions. This role requires in-depth knowledge of RNA therapeutic drug design and development methods from Target Identification to Candidate Selection. The responsibilities for this role are the following:

• Deliver state of art methodologies and capabilities to the design and optimization of therapeutics oligonucleotides by applying bio/cheminformatics techniques, the latest machine learning and AI algorithms.
• Play a critical role in the development of an RNA informatics and computational platform from discovery to development - conceptualize approaches, identify capability gaps, and set priorities to accelerate GSK's oligo research and development.
• Design a data environment for the therapeutic oligo platform from mechanism of action, sequence optimization through to synthesis and analytics
• Contribute to on-going portfolio projects within RNA therapeutics support teams through target identification through to candidate selection.
• Represent RNA therapeutics as a technical/scientific lead on cross-functional research teams that include discovery, development and research IT organizations.
• Drive the evaluation of external and internal capabilities and facilitate collaborations with external partners.
  Why You? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals:
  • A PhD or masters in computer and information sciences, cheminformatics, computational chemistry or related field with at least five years of experience in RNA drug discovery within or intersecting with the pharmaceutical or biotech industry.
  • Demonstrated track record of innovation in enveloping/delivering innovative methodologies, tools and applications in bio/cheminformatics and machine-learning.
  • Proven experience in processing, organizing, analyzing and visualizing complex data and information from disparate sources and ability to extract insight from data.
  • Track record of successful leadership, including training, developing, and managing talent.
  • Ability to build, motivate and inspire high performing teams, as well as effectively collaborate with cross-functional teams.
  • Demonstrated effective organizational skills, including ability to set, prioritize and achieve research goals.
  • Current presence or willing to relocate to Boston vicinityPreferred Qualifications & Skills:If you have the following characteristics, it would be a plus:
    • Ability to matrix with a team of multi-discipline experts including biology, chemistry, safety assessment, computational sciences, clinical scientists, translational scientists, and others.
    • Experience working with Cloud (AWS) and High-Performance Computing.
    • Experience in one or more of the following areas: cheminformatics, computational chemistry and machine-learning.
    • Extensive experience in solving scientific problems using programming languages (c++/python/php/javascript/---).
    • First-hand experience of all phases of early drug discovery from target validation to candidate selection. Understands the entirety of R&D across discovery and development.
    • Demonstrated effective communication and negotiation skills for a wide variety of audiences, including laboratory analysts and senior management.#LI-GSKGSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. -GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site. Similar Jobs (5) Head of Oligo Platform Biology locations USA - Massachusetts - Cambridge time type Full time posted on Posted Today Head of Oligo Platform Chemistry locations USA - Massachusetts - Cambridge time type Full time posted on Posted Today About Us We are a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site .

Keywords: GlaxoSmithKline, Cambridge , Head of Design and Informatics, Other , Cambridge, Massachusetts