Research Associate II - Metabolomics
Company: Broad Institute
Posted on: March 15, 2023
Research Associate II - Metabolomics page is loaded Research
Associate II - Metabolomics Apply locations Cambridge, MA time type
Full time posted on Posted 2 Days Ago job requisition id 34730 Job
Description The Broad Institute of MIT and Harvard seeks an
individual to join the Metabolomics Platform . This is a rare
opportunity to be a part of dynamic team consisting of experts in
analytical biochemistry, computational biology, and clinical
medicine. We are seeking a highly motivated team member who will
carry out LC-MS-based metabolite profiling analyses toward
completing research aims of the lab. We are looking for an
enthusiastic, self-motivated, and highly organized individual who
can thrive in a fast-paced environment and can interact well with
others as part of a team. Excellent written and oral communication
skills are required. - CHARACTERISTIC DUTIES
- Receives direction from the platform leader and other senior
members of the group to address major research goals of the lab.
Uses knowledge and technical expertise in sample preparation,
separation and analysis by mass spectrometry to complete research
projects that support the lab's projects.
- Receives biological samples from collaborators, organizes
- Responsible for precise preparation of samples from tissues
and/or biofluids using a variety of sample preparation techniques
(e.g. liquid-liquid extraction, SPE), May help to produce and
isolate samples using cell culture techniques and subcellular
- Carries out detailed LC-MS analyses of complex, biologically
derived small molecule mixtures. Follows established protocols, is
responsible review and integration of peak, and performs quality
control. Tracks and compiles results.
- Operates and maintains one or more LC-MS system (orbitrap and
triple quadrupole MS systems) for endogenous small molecule
separation, identification and quantification.
- Orders chemical standards, creates stock solutions, and helps
maintains inventory of standards.
- Helps ensure that laboratory tools and supplies, such as
software, instrument spare parts, lab reagents, etc., are in place
in accordance with project requirements.
- Attends weekly team meetings to present results, plan projects
and experiments, and to ensure that projects support current team
goals in a dynamic environment.
- Prepares detailed technical documents describing procedures and
- Other related tasks as required.QUALIFICATIONS
- Bachelor's degree in Chemistry, Biochemistry or similar and 2+
years of experience in a research laboratory.
- Experience using LC-MS for small molecule analysis, experience
in MS-based metabolite profiling is desired
- Must possess demonstrated ability and knowledge to design and
conduct research independently.
- Experience using Microsoft Office required. Experience using
mass spectrometry software and data analysis tools desired.
- Excellent communication skills and the ability to interact
professionally with all levels of staff and external contacts in a
fast-paced environment required.The Broad Institute will not offer
visa sponsorship for this opportunity. All qualified applicants
will receive consideration for employment without regard to race,
color, religion, sex, sexual orientation, gender identity, national
origin, disability or protected veteran status. EEO is The Law -
click here for more information Equal Opportunity Employer
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Keywords: Broad Institute, Cambridge , Research Associate II - Metabolomics, Other , Cambridge, Massachusetts
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