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Senior Scientist - Human Genetics

Company: Takeda Pharmaceutical
Location: Cambridge
Posted on: November 25, 2022

Job Description:

By clicking the Apply button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Senior Scientist, Human Genetics where you will lead human genetics efforts using public and proprietary data. You will have the opportunity to contribute to external collaborations linking genetic data to longitudinal phenotypic data from diverse populations, and you will closely work with colleagues in various functions across the organization to generate impactful insights from human Omics data to advance the pipeline in Neurosciences, Gastro-intestinal diseases, Rare diseases and Plasma-derived therapies.As part of the Human Genetics in the Genetics and Systems Biology group, you will report to the Director Statistical Genetics and work with Neurosciences, Gastro-intestinal diseases, Rare diseases and Plasma-derived therapies. How you will contribute:

  • Establish an influential and collaborative role within biology and disease-oriented project teams by contributing to the design, analysis and interpretation of genetic studies to inform target validation, pre-clinical safety, population stratification, clinical safety.
  • Work with a community of human geneticists to implement a human genetics roadmap and strategy and enhance integrative analytic pipelines.
  • Establish and lead external collaborations to implement emerging technologies and/or interrogate relevant biomedical datasets with in-depth genetic and health information
  • Prepare and present comprehensive technical or project reports to internal and external audiences. Minimum Requirements/Qualifications:
    • PhD with 3+ years of postdoctoral experience in human genetics research.
    • Solid experience with population genetics (GWAS/eQTL/pQTL analyses, fine-mapping and colocalization, WES/WGS sequencing data analyses, rare variants statistical analyses, Mendelian randomization) is required.
    • Experience with pathway-based approaches, multivariate analyses, polygenic risk score analyses, pharmacogenomics, machine learning and/or quantitative analysis of medical imaging data desired.
    • Strong scientific understanding of molecular biology and genomics, and ability to interpret genetic findings in disease context
    • Familiarity with pharmaceutical R&D processes and one or more diseases areas of interest of Takeda (rare diseases, neuroscience, gastroenterology and immunology) desired
    • Excellent communication, presentation and interpersonal skills
    • Independent, highly collaborative with ability to work in cross-functional and diverse team environment
    • Solid knowledge of Unix, command lines interfaces, and fluency in common Scripting and/or programming language (eg R, Python, Perl, Java, C/C+)
    • Experience with parallel computing and cloud computing What Takeda can offer you:
      • Comprehensive Healthcare: Medical, Dental, and Vision
      • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
      • Health & Wellness programs including onsite flu shots and health screenings
      • Generous time off for vacation and the option to purchase additional vacation days
      • Community Outreach Programs and company match of charitable contributions
      • Family Planning Support
      • Flexible Work Paths
      • Tuition reimbursement More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Base Salary Range: $130,200 - $186,000, based on candidate professional experience level. Employees may also be eligible for Short Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy. In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations USA - MA - Cambridge - Binney St Worker Type Employee Worker Sub-Type Regular Time Type Full time

Keywords: Takeda Pharmaceutical, Cambridge , Senior Scientist - Human Genetics, Other , Cambridge, Massachusetts

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