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Scientist/Senior Scientist

Company: ------------
Location: Cambridge
Posted on: November 23, 2022

Job Description:

Scientist/ Senior Scientist
In this Scientist position, you will join the Exploratory Biology team to scientifically mature project proposals from various Therapeutic Areas. The responsibilities include but are not limited to: (1) developing a thorough understanding of target structure and function; (2) supporting development of best antibody, small molecule and cell therapy approaches by building required biological assays, systems, and cell lines; (3) efficient use of extensive expertise spread across organization and at contract research organizations.
The highly qualified candidate is expected to interface with project leaders, contribute to the assessment of the projects' needs for target characterization and relevant assay formats, and conduct non-routine experiments in a fast-paced multitasking environment.
About this Role:
This position offers you an exciting opportunity to engage in the discovery of novel biotherapeutics for unmet medical needs. The ideal candidate for this role would thrive while:

  • Working under limited supervision with a high level of autonomy
  • Designing, performing and interpreting in vitro and ex vivo experiments, including but not limited to: flow cytometry and sorting, ELISA, tumor cell killing, NK cell based killing assay, immune cell isolation from whole blood or tissues, reporter assays, transcription assays (such as quantitative RT-PCR), transfection and cloning of stable cell lines, Western blot. Ability to troubleshoot where necessary.
  • Staying up-to-date with the literature in your field.
  • Being an independent thinker and effective communicator
  • Driving the analysis of highly complex issues and identification of significant improvements, changes or adaptations of existing methods and techniques
  • Developing research solutions that require extensive synthesized analysis, detailed investigation, and uncovering new approaches
  • Influencing or persuading others to accept new ideas that challenge the status-quo
  • Frequently interacting with senior internal and external colleagues often requiring coordination across multiple functions and groups
  • Collaborating with external partners and networks
    The ideal candidate has:
    Ph.D. degree in life sciences (immunology, molecular biology, biochemistry, or a related discipline)
    • Cutting edge laboratory experience with molecular and functional characterization of signaling and metabolism pathways in the fields of immunology, oncology, or immuno-oncology
    • Experience in design, execution and analysis of in vitro pharmacology studies to assess receptor/ligand interactions, or complex in vitro functional assays to assess efficacy of antibody or cell-based therapeutics.
    • Established scientific reputation through published work in peer-reviewed journals, participating in patent preparation or oral presentations
    • Strong organizational and communication skills, ability to effectively lead cross-disciplinary teams, lead others in the preparation of scientific publications, patents, journals and presentations, lead the proper documentation of new inventions and discoveries and interpret and integrate data to make recommendations for critical discovery/technology project decisions
      What we offer at Simcere:
      • An innovation-driven culture that puts science at the forefront of everything we do.
      • A dynamic, diverse, and inclusive team of experienced scientists applying their skills to some of the most impactful problems in human health.
      • Competitive salary and equity compensation, along with premium health, dental, and vision benefits.

Keywords: ------------, Cambridge , Scientist/Senior Scientist, Other , Cambridge, Massachusetts

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