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Scientist - II (Associate)

Company: Experis
Location: Cambridge
Posted on: September 20, 2022

Job Description:

Experis, a ManpowerGroup company, has an exciting contract opportunity with one of our key clients, a global biopharmaceutical company that is engaged in the discovery, development and manufacturer of healthcare products.Job Description:Scientist - II (Associate)Location: Cambridge MADuration: 12 MonthsQualifications:Education and Experience: * BS/BA degree in Biology, Neuroscience, Molecular Biology Bioengineering, Biotechnology or equivalent degree with at least 1+ year of industry or academia experience Required skills and competencies: * Strong general knowledge of cell culture methods and sterile technique. * Experience working immortalized cells lines, primary rodent neurons and glia (e.g. microglia) human iPS-derived CNS cell models including microglia and neurons. * Understanding of standard cell transfection techniques using lipid-based and electroporation methodology * Cell staining methods including Immunofluorescence and cell masks or cell structural staining methods. * Some experience with method optimization, troubleshooting and strong critical thinking skills * Proven experience in image acquisition and strong microscopy skills and strong working knowledge of mouse neuroanatomy * Ability to work independently on data analysis including a practical knowledge of statistics.Preferred skills//Nice to have: * Experience with plate based high content imaging microscopy * Live cell imaging * Demonstrated experience with quantitative image analysis. * Practical application of CRISPR editing technology and siRNA knockdown strategies * Working understanding of biochemical and molecular biology techniques including protein and RNA extraction, quantitation and detection methods such as western-blot, ELISA and qPCR * Experience with cellular signaling and functional studies including phagocytosis and/or cell motility measures * Strong oral, written and presentation skills with ability to explain concepts clearly in lab and small team settings.Responsibilities: * The Neuroimmunology team is seeking a motivated and technically-skilled individual with strong CNS cell biology skills to join our Cambridge-based team. * Candidates will be able to work to collaborate with colleagues across diverse functional areas including genetics, chemical biology, immunology and pharmacology. * Primary responsibilities include culturing of stable cell lines, primary and iPS-derived microglia to support the study of disease associated functions and phenotypes that will support identification and validation of novel therapeutic targets to treat neurodegenerative diseases. * The responsibilities of the Neuroimmunology team member include: assist in developing and performing disease-relevant cell-based functional assays and perform high content imaging, biochemical and molecular profiling techniques. * The successful candidate will be able to communicate data clearly and concisely to the appropriate teams and stakeholders and thrive in a team environment.APPLY TODAY!

Keywords: Experis, Cambridge , Scientist - II (Associate), Other , Cambridge, Massachusetts

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