Principal Research Associate

Company: Skills Alliance
Location: Cambridge
Posted on: June 23, 2022

Job Description:

Skills Alliance is representing a groundbreaking biotech startup who are dedicated to developing transformative medicines which can strike right at the heart of disease, while also focusing on keeping them broadly accessible to the patients who need them most!As a result of tremendous company growth, their Cambridge, MA location has an immediate need for a talented Principal Research Associate.DUTIES AND RESPONSIBILITIES

• Fully lab-based role, providing technical support and leadership for DNA cloning efforts, and other molecular biology activities.
• Provide technical insights and employ modern cloning technologies (i.e. Gibson/HiFi Assembly, Golden Gate/MoClo, LIC) to generate new gene therapy vectors.
• Enable and perform high-throughput cloning to facilitate pooled selection strategies; Generate high-diversity barcoded plasmid libraries.
• Comply with standard laboratory practices and company policies, including strict notebook documentation and biosafety policies.
• Contribute to the overall company mission and culture.QUALIFICATIONSBasic Qualifications
  • Bachelor's degree in biology and 6+ years of experience or an equivalent combination of education and experience required.
  • Extensive hands-on experience of modern molecular biology techniques, as well as with molecular analytical tools for plasmid QC.
  • Previous experience in pooled DNA cloning.
  • Excellent bench skills with attention to detail and high standards for data integrity and quality.Preferred Qualifications
    • Deep knowledge of gene expression regulations in eukaryotic expression systems and experience of using these elements to optimize gene expression.
    • Experience designing lentiviral transfer plasmids.If this exciting opportunity sounds of interest to you, please apply with your most updated resume and we will be in contact with you.

Keywords: Skills Alliance, Cambridge , Principal Research Associate, Other , Cambridge, Massachusetts