Senior Scientist, In vitro/ Ex vivo - Ophthalmology

Company: Novartis
Location: Cambridge
Posted on: May 13, 2022

Job Description:

60 million! That is how many people are affected globally by glaucoma. This can lead to progressive damage to retinal ganglion cells and the optic nerve and may lead to blindness.

At Novartis, we are developing new therapies to help control glaucoma disease progression by lowering eye pressure and by protecting retinal neurons to treat this silent thief of sight.

We are looking for an experienced scientist to join our Ophthalmology Department to support the discovery and development of innovative glaucoma treatments.

What you'll be doing:

Applying cell-based assays to support the discovery, validation and characterization of novel glaucoma therapies and handling/processing of ex-vivo tissues for pharmacodynamics/biomarker assessments. Independently perform experiments, troubleshoots issues, evaluate data, generate reports, and present data at internal forums.
Contribute to the design and optimization of experiments and stay current on literature and technological advances. Collaborate with cross-functional teams on target discovery and drug development projects.
Assist in general laboratory maintenance.


EEO StatementThe Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.Minimum requirementsWhat you'll bring to the role:

• MS or BS in Biology or related field with 3-5+ years of full time academic or industry laboratory experience
• Demonstrated proficiency in a broad range of molecular/ protein/ cellular assays and analysis (such as ELISA, Western blotting, qPCR and fluorescent microscopy imaging)
• Hands-on experience in culturing primary cells or ESC/iPSC-derived cells
• Familiarity with molecular biology, gene editing, cell engineering or AAV/Lenti-viral vector
• Highly motivated self-starter and problem-solver with a demonstrated ability to adapt quickly and work independently
• Ability to thrive in a fast-paced matrix research environment
• Demonstrated strong communication skills, independence and attention to details
• Training in ophthalmology, neuroscience, immunology, cell biology or related fields preferred
• Familiarity with tissue microdissection, complex phenotypic assays, explant culture, and complex cell culture systems is a plus
  Why consider Novartis?
  
  Transformative medicines need transformative thinking. We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment.
  
  Where you're given opportunities to explore the power of digital and data. Where you are empowered to risk failure by taking smart risks, and where people who share your determination to tackle the world's toughest medical challenges surround you.
  
  We are Novartis. Join us and help us reimagine medicine.
  
  Commitment to Diversity & Inclusion:
  Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.
  
  Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/networkDivisionNIBRBusiness UnitOPHTHALMOLOGYCountryUSAWork LocationCambridge, MACompany/Legal EntityNIBRIFunctional AreaResearch & DevelopmentJob TypeFull TimeEmployment TypeRegularShift WorkNoEarly TalentNo

Keywords: Novartis, Cambridge , Senior Scientist, In vitro/ Ex vivo - Ophthalmology, Other , Cambridge, Massachusetts