Research Associate, Stem Cells
Company: QurAlis
Location: Cambridge
Posted on: May 13, 2022
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Job Description:
ABOUT THE COMPANY
QurAlis is applying precision medicine to advance a novel
therapeutic pipeline for the treatment of amyotrophic lateral
sclerosis (ALS), frontotemporal dementia (FTD) and other
neurodegenerative diseases. Our stem cell technologies can test
efficacy of various therapies and provide a transitional bridge to
the clinic enabling target validation, discovery, and molecule
selection. We are advancing three antisense and small molecule
programs addressing sub-forms of ALS that account for most
patients. Together with a world-class network of thought leaders,
drug developers, and patient advocates, our growing team is at the
leading edge of neurodegenerative research and development.
We are honored to have won the Fierce15 and the New England Venture
Capital Association's NEVY award for Best Emerging Life Science
Company in New England's startup ecosystem. -We are pioneers in
neurodegenerative disease biology, stem cell and antisense
oligonucleotides (ASO) technology, biomarkers, and small molecule
design. -We are honest and empathetic to our patient community,
science, colleagues, and ourselves, sharing a common passion to
urgently discover new medicines for ALS and FTD. -We represent a
diversity of backgrounds and value collaboration. -We believe that
success in treating neurodegenerative diseases will be achieved by
being precise - targeting the right patients, identifying the right
disease mechanism, and carefully developing disease-modifying,
clinically meaningful therapies to improve the lives of
patients.
Summary of Position
QurAlis is seeking a highly motivated Research Associate to support
and execute its cutting-edge stem cell biology models. The Research
Associate will work closely with the QurAlis scientific and
management teams to perform studies in a high quality and
scientifically rigorous fashion.
Primary Job Responsibilities:
Cell line maintenance, expansion, and cryopreservation of human
induced pluripotent stem cells (iPSCs)
Differentiation of iPSCs into specialized neurons and glia for
target validation and drug discovery efforts
Characterization and quality control of iPSCs and iPSC-derived
neurons using routine cellular and biochemical assays
(immunofluorescence, imaging assays, microscopy, western blotting,
qPCR).
Process, organize, and summarize data using electronic lab
notebook. This includes detailed lab records of experiments, cell
line tracking and reagent management.
Ability to improve and develop new protocols/new assays and address
key questions
Works under minimal supervision for routine activities and moderate
supervision for non-routine activities
Assist in maintenance of the cell culture facility/equipment, and
the generation and implementation of standard operating
procedures
Organize an effective working schedule and prioritize tasks
appropriately
Perform other duties and responsibilities as directed.
Must have scheduling flexibility to enable weekend and holiday work
rotations
Minimum Qualifications Required
A Bachelor's degree in the biological sciences with 2+ years lab
experience or master's degree with 1+ year lab experience
Prior experience with mammalian cell culture is required. Stem cell
experience strongly preferred
High performer, willingness and motivation to learn new skills and
mastery
Sharp attention to detail and ability to multitask
Strong communication skills including ability to follow written and
oral instructions
Ability to interact and collaborate successfully in
cross-functional teams
Must be authorized to work legally in the United States.
Keywords: QurAlis, Cambridge , Research Associate, Stem Cells, Other , Cambridge, Massachusetts
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