Research Scientist
Company: Rangam Consultants Inc.
Location: Cambridge
Posted on: May 12, 2022
Job Description:
Research Scientist - (Early drug discovery)
Job Location: Cambridge, MAThe Research Scientist will join the
Early Drug Discovery group at client in Cambridge, MA and aide in
the advancement of early-stage therapeutic targets. The position
will utilize genome engineering, mechanistic biology, assay
development, and other cutting-edge technologies to validate tumor
intrinsic targets and support drug discovery pipeline.
- The qualified candidate is a highly motivated, interactive, and
creative individual that possesses the ability to work across a
highly matrixed environment and aid the advancement of the next
wave of targets into preclinical drug development.
- The candidate will be expected to effectively collaborate with
colleagues across discovery oncology including the exploratory
pharmacology, drug discovery and translational research
groups.
- The position requires the ability to design, iterate, and lead
several key project initiatives and demonstrate critical thinking
to challenge self and others.
- The successful candidate will demonstrate clear and
professional verbal and written communication skills and will be
capable of communicating these results across multidisciplinary
teams.Qualifications and key responsibilities
- A B.S. with a minimum of 7 years, an M.S. with a minimum of 5
years, or a PhD with a minimum of 3 years of academic/industrial
experience and demonstrated expertise in cancer biology and
genetics, oncogenic signaling or DNA damage response pathways
- Demonstrated independence in experimental design, execution,
data analysis, and troubleshooting are required.
- Strong scientific and hands-on experience using a wide range of
cellular and molecular biology techniques, including tissue
culture, flow cytometry, western blotting, Immunoprecipitation,
development of reporter assays, MSD, ELISA, use of genetic
perturbation techniques (eg shRNA,siRNA CRISPR-mediated genome
editing), qRT-PCR, cell proliferation assays, lentivirus generation
and transduction are required.
- Experience in forward and reverse genetic screening followed by
target validation studies to elucidate mechanistic biology and
oncogenic SAR is strongly preferred.
- Proficiency in utilizing software such as Graph Pad, FlowJo,
Microsoft office etc. for data analysis and figure generation is
required.
- Ability to lead, design, and execute on project initiatives and
operates to a High Standard. Attention to detail with excellent
organizational and record keeping skills is a requirement.
- Excellent interpersonal skills with the ability to interact
effectively with people, internally and externally, is
required.
Keywords: Rangam Consultants Inc., Cambridge , Research Scientist, Other , Cambridge, Massachusetts
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