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Research Scientist

Company: Rangam Consultants Inc.
Location: Cambridge
Posted on: May 12, 2022

Job Description:

Research Scientist - (Early drug discovery)

Job Location: Cambridge, MAThe Research Scientist will join the Early Drug Discovery group at client in Cambridge, MA and aide in the advancement of early-stage therapeutic targets. The position will utilize genome engineering, mechanistic biology, assay development, and other cutting-edge technologies to validate tumor intrinsic targets and support drug discovery pipeline.

  • The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment and aid the advancement of the next wave of targets into preclinical drug development.
  • The candidate will be expected to effectively collaborate with colleagues across discovery oncology including the exploratory pharmacology, drug discovery and translational research groups.
  • The position requires the ability to design, iterate, and lead several key project initiatives and demonstrate critical thinking to challenge self and others.
  • The successful candidate will demonstrate clear and professional verbal and written communication skills and will be capable of communicating these results across multidisciplinary teams.Qualifications and key responsibilities
    • A B.S. with a minimum of 7 years, an M.S. with a minimum of 5 years, or a PhD with a minimum of 3 years of academic/industrial experience and demonstrated expertise in cancer biology and genetics, oncogenic signaling or DNA damage response pathways
    • Demonstrated independence in experimental design, execution, data analysis, and troubleshooting are required.
    • Strong scientific and hands-on experience using a wide range of cellular and molecular biology techniques, including tissue culture, flow cytometry, western blotting, Immunoprecipitation, development of reporter assays, MSD, ELISA, use of genetic perturbation techniques (eg shRNA,siRNA CRISPR-mediated genome editing), qRT-PCR, cell proliferation assays, lentivirus generation and transduction are required.
    • Experience in forward and reverse genetic screening followed by target validation studies to elucidate mechanistic biology and oncogenic SAR is strongly preferred.
    • Proficiency in utilizing software such as Graph Pad, FlowJo, Microsoft office etc. for data analysis and figure generation is required.
    • Ability to lead, design, and execute on project initiatives and operates to a High Standard. Attention to detail with excellent organizational and record keeping skills is a requirement.
    • Excellent interpersonal skills with the ability to interact effectively with people, internally and externally, is required.

Keywords: Rangam Consultants Inc., Cambridge , Research Scientist, Other , Cambridge, Massachusetts

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