Senior Scientist, Single Cell & Systems Biology
Company: Sanofi
Location: Cambridge
Posted on: May 12, 2022
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Job Description:
Position Overview:The Discovery and Validation group in the
Single-Cell Biology Cluster, Precision Medicine and Computational
Biology at Sanofi is focused on delivering first-in-class medicines
to patients by deconstructing the mechanisms of disease into
cellular building blocks and advancing first-in-class therapeutics
for precision targeting of pathogenic cell types. Our efforts have
achieved significant internal and external visibility and media
presence.We are seeking a highly competent, independent, proactive,
driven and well-organized Senior Scientist to build on our present
achievements and ensure our future success. The ideal candidate
will derive professional satisfaction from:Generating hypotheses on
how pathogenic cell type/state drive diseases (especially in
immunological, neurological, and rare disease areas) by leveraging
internal and external single-cell data.Applying established
single-cell transcriptomic & proteomic methods to understand
disease and drug mechanisms.Using analytic tools and workflows to
uncover the activity of disease-relevant genes and pathways in
pathogenic cell types.Leading projects involving internal
experiment design and data analytics as well as outsourcing of
established workflows and/or complex follow-up mechanistic assays
(organoid, CRISPR, proteomics)Collaborating with academic,
industry, and internal partners on method development and
disease-focused scientific studies.Leading and contributing to
high-profile presentations and publications.S/he should have the
ability to creatively lead projects and coordinate scientific
activities, summarize and present results, and establish their
relevance to key decision points in the drug discovery process.
Opportunities to mentor interns, and junior scientists may be
available.Qualifications:Ph.D. in Systems Biology, Immunology,
Neuroscience or related discipline, with postdoctoral training at a
solid academic institution and/or equivalent industry experience
(exceptional candidates with the right background and skills may be
considered right after Ph.D.)A track record of productivity,
innovation and impact (publications, patents)Broad experience with
cell-based assays and molecular techniques such as primary cell
isolation/culture, multicolor flow cytometry, cell sorting, ELISA,
qPRC, RNA and DNA isolation, immunoblot.Extensive hands-on
experience and deep knowledge of single-cell experimental and/or
analytical workflows (10X, InDrop, SeqWell, CITE/REAP-seq, etc).
Ability to use R or python based analytic workflows a definite
plus.Excellent communication, organizational, interpersonal and
team skills; track record of success working collaboratively across
disciplines.What we offer:A combination of start-up mindset and big
pharma stability.An academic spirit of curiosity and potential for
direct impact on people's lives.An environment fostering individual
growth, ensuring visibility and celebrating achievement.Flexible,
goal-oriented work schedule, excellent work-life balance, allowing
you to thrive both professionally and personally.At Sanofi R&D
North America, we deliver meaningful solutions for patients. We
transform science into breakthrough, best-in-class and
first-in-class medicines and vaccines. We believe in creating a
diverse and inclusive workforce - and workplace - which brings
together the collective brainpower of over 2,000 colleagues and
provides you with an exciting place to grow and develop. We set the
bar high, and we deliver. Join us and together we will build on our
trusted legacy of breakthroughs for society.Sanofi Inc. and its
U.S. affiliates are Equal Opportunity and Affirmative Action
employers committed to a culturally diverse workforce. All
qualified applicants will receive consideration for employment
without regard to race; color; creed; religion; national origin;
age; ancestry; nationality; marital, domestic partnership or civil
union status; sex, gender, gender identity or expression;
affectional or sexual orientation; disability; veteran or military
status or liability for military status; domestic violence victim
status; atypical cellular or blood trait; genetic information
(including the refusal to submit to genetic testing) or any other
characteristic protected by law.As a healthcare company and a
vaccine manufacturer, Sanofi has an important responsibility to
protect individual and public health. All US based roles require
individuals to be fully vaccinated against COVID-19 as part of your
job responsibilities.Fully vaccinated, according to the CDC, an
individual is considered to be "fully vaccinated" fourteen (14)
days after receiving (a) the second dose of the Moderna or Pfizer
vaccine, or (b) the single dose of the J&J vaccine. Fully
vaccinated, for new Sanofi employees, is to be fully vaccinated 14
DAYS PRIOR TO START DATE. GD-SALI-SAPDNAt Sanofi diversity and
inclusion is foundational to how we operate and embedded in our
Core Values. We recognize to truly tap into the richness diversity
brings we must lead with inclusion and have a workplace where those
differences can thrive and be leveraged to empower the lives of our
colleagues, patients and customers. We respect and celebrate the
diversity of our people, their backgrounds and experiences and
provide equal opportunity for
all.PDN-95f06d53-86dd-4d5e-b250-a0ac92bf53d6
Keywords: Sanofi, Cambridge , Senior Scientist, Single Cell & Systems Biology, Other , Cambridge, Massachusetts
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