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Investigator I (LC/MS Protein Biochemistry)Job Summary:Major Responsibilities:Minimum Requirements

Company: CSL Limited
Location: Cambridge
Posted on: November 19, 2021

Job Description:

Investigator I (LC/MS Protein Biochemistry) United States of America R-142547 0606 Seqirus Inc About CSL With operations in 35+ nations and -27,000 employees worldwide, CSL is driven to develop and deliver a broad range of lifesaving therapies to treat disorders such as hemophilia and primary immune deficiencies, and vaccines to prevent influenza. Our therapies are also used in cardiac surgery, organ transplantation and burn treatment.

CSL is the parent company of CSL Behring and Seqirus. CSL Behring is a global leader in the protein biotherapeutics industry, focused on bringing to market biotherapies used to treat serious and often rare conditions. CSL Behring operates CSL Plasma, one of the world's largest collectors of human plasma, which is used to create CSL's therapies. Seqirus is one of the largest influenza vaccine companies in the world and is a transcontinental partner in pandemic preparedness and a major contributor to the prevention and control of influenza globally.

We invite you to take a look at the many career possibilities available around the globe and consider building your promising future at CSL by becoming a member of our team! Job Description Job Summary: This position is responsible to develop LC/MS based methods to characterize larger molecules eg. protein and DNA/RNA, including but not limited to expression levels and identifying the post-translation modifications. The ideal candidate would integrate proteomics with functional studies to characterize the biology of different vaccine candidates. Major Responsibilities: Conduct biophysical/chemical methods for protein characterization Develop mass spectrometry-based assays for quantification of proteins

  • Develop MS-based assays for characterization of proteins/RNA/lipids
  • Identify separation and analytical methods for evaluation of lipids/RNA
  • Collaborate across the research and early development space to integrate proteomics processes
  • Collaborate across departments to identify and meet the proteomics need Documentation and presentation of scientific results.
    • Write experimental protocols and prepare internal reports. Maintain lab notebooks.
    • Collaborate with project teams, present research results and contribute to technical advancements and publications.
    • Maintain functional laboratory equipment and follow HSE regulation. Other job duties that may be assigned from time to time.
      • Support other functions and other divisions when needed.
      • Ph.D. degree in Chemistry/Biochemistry/bio/chemical engineering or related biological sciences.
      • Ph.D. with 1+ years of academic or pharmaceutical/biotech experience in biochemistry.
      • Experience with chromatography techniques (RP), and the development of processes for characterization of biomolecules based on LC/MS/MS
      • Experience with quantitative proteomics based on isotopically-labelled-peptides
      • Experience with post-acquisition data analysis software and statistical analysis of mass spectrometry data
      • Experience with protein quantification techniques including but not limited to iTRAQ/TMT/SILAC
      • Desire to work under a collaborative and fast pace environment is preferred
      • Organizational, written and oral communication skills and ability to work in teams is required Share: State/Province Massachusetts City Cambridge Primary Location Seqirus USA - MA - Cambridge Full Time/Part Time Full Time Equal Opportunity Employer CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please click below.

Keywords: CSL Limited, Cambridge , Investigator I (LC/MS Protein Biochemistry)Job Summary:Major Responsibilities:Minimum Requirements, Other , Cambridge, Massachusetts

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