Research Associate/Senior Research Associate, Translational Sciences

Company: THIRD ROCK VENTURES, LLC
Location: Cambridge
Posted on: November 19, 2021

Job Description:

Research Associate/Senior Research Associate, Translational Sciences at Magenta Therapeutics Magenta Therapeutics is a clinical-stage biotechnology company developing therapeutics to reset the immune system to cure more patients with devastating and life-threatening diseases. This immune reset approach can be applied through stem cell transplant to multiple diseases, including autoimmune diseases, such as multiple sclerosis and systemic sclerosis; blood cancers, such as acute myeloid leukemia; and genetic diseases, such as sickle cell disease. Magenta's comprehensive approach to precision immune system reset will transform many aspects of the transplant process, aiming to make it safer and more effective. Our culture is fueled by a driven, passionate group of people committed to making a difference, seizing opportunities for maximum impact, and pursuing progress for the patients we seek to serve. Working in the Translational Sciences group, the Research Associate/Senior Research Associate will contribute to efforts to progress programs from candidate nomination to the clinic, experimentally characterize Magenta medicines, and discover and validate novel biomarkers for our research- and clinical-stage programs. The position requires experience in molecular biology and assay development, optimization, and analysis. It is an exciting and unique opportunity to bridge discovery and clinical research to impact patients' lives. You are perfect for this role if you are engaged by and want to be responsible for:

• Designing, planning, and executing a broad range of molecular and cellular biology assays to functionally characterize pre-clinical and clinical samples, broaden the mechanistic understanding of our medicines, and support new target and translational biomarker identification.
• Independently developing, troubleshooting, and analyzing complex experiments.
• Working with entire research team on molecular and genome editing studies.
• Analyzing, documenting, and regularly presenting scientific data to the team.
• Keeping current on scientific literature to implement learnings in experimental design. We would be thrilled if you brought the following with you:
  • BS or MS in Biology/Immunology with a minimum of 2 years relevant research experience in molecular or cell biology.
  • Expertise in molecular biology (e.g. PCR) and gene editing (e.g. CRISPR) techniques
  • Experience in mammalian/primary cell culture, including human and mouse HSCs and/or immune cells.
  • Experience in flow cytometry and cell sorting, ELISA/MSD, and HSC/immune cell functional assays.
  • Must be a creative, organized, motivated self-starter, capable of independent research, data analysis, and maintenance of clear experimental records.
  • The position requires excellent communication skills and the ability to work in a highly collaborative, team-oriented environment. Successful leaders and contributors within Magenta are:
    • Driven. You will be focused on the achievement of Magenta's mission and major corporate goals.
    • Results-focused. Demonstrated record of exceeding stretch goals, and willing to bring creative problem-solving skills to challenges along the way
    • Intuitive.--You will enjoy learning and being involved in the content of our whole business, thriving on a very fast-paced and growing business
    • Collaborative. You will have demonstrated the ability to achieve objectives across complex projects and organizational structures
    • Process-oriented, yet flexible.--You will appreciate and be able to create and drive process, while also recognizing when flexibility is needed.
    • Transparent and Articulate. You will have the ability to communicate clearly and concisely with all stakeholders
    • Independent.--You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the company
    • A role model for the company's cultural pillars; Courage, Commitment & Excellence At Magenta, we celebrate our differences. We value the power of a diverse array of folks who bring all of themselves to their work. We embrace cultural, cognitive, social, and professional diversity because we know the only way we're going to make new cures possible is by working together. 29 Newbury Street
      3rd Floor
      Boston, MA 02116
      P (617) 585-2000

Keywords: THIRD ROCK VENTURES, LLC, Cambridge , Research Associate/Senior Research Associate, Translational Sciences, Other , Cambridge, Massachusetts