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Scientist, In Vivo Viral Delivery

Company: Beam Therapeutics Inc.
Location: Cambridge
Posted on: June 12, 2021

Job Description:

We are currently seeking a self-motivated and technically competent research Scientist to join our team. He/She will support our exploratory research in disease target validation using gene editing tools in our in vivo viral delivery group. The candidate will be responsible for conducting preclinical animal studies to support drug development candidates. They will also perform downstream in-vitro assays.

Primary Responsibilities:

  • Manage 1-3 research associates to generate robust pharmacological and disease relevant biological data.
  • Design, plan, and execute in-vivo studies in rodents for CNS, ophthalmology, and exploratory indications.
  • Support the implementation and validation of new animal models.
  • Strong background in molecular biology.
  • Experience with in-vitro assays; including ELISA, Luminex, flow cytometry, and qPCR.
  • Experience with cell culture in primary cells and cell lines.
  • Analyze data using software including FlowJo, Excel, and GraphPad Prism.
  • Follow IACUC protocols and standard operating procedures (SOPs).
  • Coordinate in vivo pharmacology research in a matrixed environment, as well as external academic.
  • Preparing and editing nonclinical protocols and reports for regulatory submissions.
  • Collaborations and an extensive network of CROs.


  • PhD with at least 2 years' experience in the biotechnology or pharmaceutical industry or BS/MS with over 10 years of relevant experience.
  • Experience with rodent models is required; including animal handling, routine injections, and necropsy.
  • Working knowledge of the central nervous system and gene therapy is desirable.
  • Experience with ELISA, flow cytometry, and qPCR.
  • Experience with cell culture and sterile technique.
  • Desire and drive to learn and understand the basic biologic mechanisms underpinning our cell and gene therapy products.
  • Experience in maintaining a laboratory notebook and following protocols.
  • Familiarity with programs such as Excel, GraphPad Prism, FlowJo, and PowerPoint for data entry, analysis, and presentation.
  • Team player with excellent oral and written communication skills and "do-what-it-takes" attitude.
  • Independently motivated, detail-oriented, and excellent problem-solving abilities.
  • Excellent organizational skills towards multi-tasking in an extremely fast-paced environment with changing priorities.

Keywords: Beam Therapeutics Inc., Cambridge , Scientist, In Vivo Viral Delivery, Other , Cambridge, Massachusetts

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