Scientist, Translational Neuropathology

Company: Biogen Idec
Location: Cambridge
Posted on: June 12, 2021

Job Description:

Company Description

Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Founded in 1978, Biogen is a pioneer in biotechnology and today has the leading portfolio of medicines to treat multiple sclerosis, introduced the first approved treatment for spinal muscular atrophy and is at the forefront of neurology research for conditions including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

Job Description

The Translational Neuropathology group at Biogen (Biomarkers, Clinical Sciences) is seeking a highly motivated and talented scientist to join a fast-paced, interdisciplinary, dynamic team engaged in translational research to enhance our human neurologic disease portfolio. The scientist will employ cutting-edge molecular and histopathologic technologies in studies of human brain tissues leading to biomarker discovery and clinical measurement strategies, target validation and understanding of disease biology. The candidate may also contribute to novel biomarker assay development for preclinical studies to advance therapeutic programs toward clinical development. The scientist will contribute to portfolio success in neurodegeneration and/or neuromuscular diseases.

Qualifications

• The ideal candidate has demonstrated a track record of high-quality productivity and rigor in pathology or neuroscience research.
• A background in translational neuroscience with a focus on neurodegeneration and/or neuroinflammation is highly desirable.
• Established knowledge of human neuroanatomy and neuropathology, and skills in histology, immunohistochemistry and in situ hybridization, will be advantageous but can also be acquired in this role.
• Basic experience in cellular and biochemical science such as standard molecular biology and protein biochemistry techniques (e.g. DNA cloning, protein purification, real-time PCR, Western blotting, immunoprecipitation, enzymatic assays) is required.
• Prior experience in one or more of the following innovative technologies is desirable: single-cell transcriptomics, spatial transcriptomics, Slide-seq/FISSEQ/seqFISH/MERFISH, proteomics, FACS/CyTOF, imaging mass cytometry or MIBI.
• Highly effective communication skills and ability to work independently or with minimal supervision in managing projects and priorities are essential. Capacity to work in a highly collaborative and cross-functional environment is required.

Education

The position requires a PhD degree in Biological Sciences or a related discipline and at least 2 years of relevant postdoctoral laboratory experience in industry or academia.

Additional Information

All your information will be kept confidential according to EEO guidelines.

Keywords: Biogen Idec, Cambridge , Scientist, Translational Neuropathology, Other , Cambridge, Massachusetts