Company: Principia Biopharma Inc.
Posted on: June 7, 2021
The Immunology and Inflammation Research and Early Development
Therapeutic Area in Sanofi is building a world-class immunology
team and is seeking highly motivated scientists to identify novel
therapies in the fields of Immune Checkpoint Biology, Autoimmunity
and Innate Immunity.
We are seeking a highly motivated Scientist to join the
Checkpoint Immunology Cluster located in Cambridge, MA
The successful candidate will have broad expertise in immunology
and cellular biology, excellent oral and written communication
skills, and the ability to learn and acquire new techniques and
methodologies. The position is a hands-on, laboratory based role.
The candidate is expected to analyze, record and report data, be
able to develop new methodologies, and execute projects with
appropriate supervision. The candidate will participate in new
targets identification and validation to support current and future
drug discovery programs. This exciting role will afford scientists
the opportunity to be intimately involved in early discovery
research and pre-clinical development.
Responsible for independently performing experiments and studies
in support of research project for drug discovery goals.
Initiate, design, direct and execute experiments, and analyze,
interpret and present results.
Support drug discovery project working with scientific platform
teams and proactively contribute to projects from discovery into
early clinical development.
Support the development of disease relevant in vitro and in vivo
Establish in vitro immunological assays to evaluate the
biological functions of target molecules in human immune cells.
Collaborate with bioinformatics and translational science team
to identify and validate the therapeutic targets.
Provide and promote support for operational excellence according
to Sanofi values and ethics.
- Prepare publications, research and clinical/regulatory
documentation in accordance with Sanofi quality standards.
- PhD or Bachelor or Master degree with minimum 12 years of
experience in human immunology and in vivo pharmacology.
Strong background in human immunology and pre-clinical
Skilled in cell culture and experience with in vitro functional
assays using human primary immune cells is highly desirable.
Broad experience with immunological and molecular principles and
techniques including primary cell isolation/culture, multicolor
flow cytometry, cell sorting, ELISA, qPRC, RNA and DNA isolation,
immunoblot and lentiviral delivery.
Experience working with preclinical animal models of immune
Excellent written and oral communication skills.
- Excellent interpersonal and team skills; track record of
success working collaboratively across disciplines.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and
Affirmative Action employers committed to a culturally diverse
workforce. All qualified applicants will receive consideration for
employment without regard to race; color; creed; religion; national
origin; age; ancestry; nationality; marital, domestic partnership
or civil union status; sex, gender, gender identity or expression;
affectional or sexual orientation; disability; veteran or military
status or liability for military status; domestic violence victim
status; atypical cellular or blood trait; genetic information
(including the refusal to submit to genetic testing) or any other
characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we
operate and embedded in our Core Values. We recognize to truly tap
into the richness diversity brings we must lead with inclusion and
have a workplace where those differences can thrive and be
leveraged to empower the lives of our colleagues, patients and
customers. We respect and celebrate the diversity of our people,
their backgrounds and experiences and provide equal opportunity for
Keywords: Principia Biopharma Inc., Cambridge , Scientist, Other , Cambridge, Massachusetts
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