Senior Associate Scientist I/II, In Vivo Pharmacology
Company: bluebird bio, Inc.
Posted on: June 7, 2021
On January 11, 2021, we announced our intent to separate our
severe genetic disease and oncology businesses into differentiated
and independent publicly traded companies. We will retain focus on
severe genetic disease (SGD) and will launch our oncology business
("Oncology Newco") as a new entity, with the completed transition
expected by the end of 2021.
ABOUT THE NEST
At bluebird, only two things matter - patients and our people.
When you join the nest, you're not just landing a new gig, you
become a part of a flock that's soaring to new heights. We're 1100+
doers, thinkers and collaborators across the globe with a strong
sense of our values and our purpose. Our innovation and
sustainability are rooted in the diversity of our teams and results
are achieved through cooperation and the incorporation of multiple
points of view. This is personal and we approach every challenge
with radical care. The time is now to rise up and recode the
science, the systems, and the status quo.
ABOUT THE FLOCK
The In Vivo Sciences flock is part of the Preclinical and
Translational Development group which works with bluebird bio's
discovery platforms and translational research teams to generate
the hypotheses, mechanism-of-action, and efficacy data that fuel
the bluebird pipeline. We also work with our clinical and
regulatory teams to generate the toxicology and biodistribution
data that is critical to translating each of bluebird's innovative
therapies safely from research into patients. In doing so, we
continuously strive towards our mission to be the biotech world's
best preclinical development organization for immunotherapy and
gene therapy. Come work with an energetic group of birds who love
rising to the challenge, as much as we love to support one another
inside and outside of the nest.
HOW YOU'LL FLY
We are seeking a highly motivated Study Lead (Senior Associate
Scientist I/II) with extensive experience planning, managing and
executing preclinical in vivo studies to support Oncology and Gene
Editing programs. As an In Vivo Sciences bird reporting to the
Associate Director, you'll help to bring more patients their
bluebird days by:
- Planning and executing in vivo efficacy, PK/PD, biodistribution
& safety studies in mouse tumor models and PBMC or stem cell
engraftment models in collaboration with research scientists.
- Establishing new animal models as needed, including pilot
studies for model development, troubleshooting, and model
- Recording and analyzing data using software including Excel,
GraphPad Prism, and Studylog.
- Preparing and presenting data to various groups within the
- Planning and coordinating with other scientists within In Vivo
Sciences and across various functions such as Research,
Translation, and Pathology to ensure efficient study execution,
sample transfer, and analysis
- Contributing to the initial and recurrent training of junior
vivarium staff members
WHAT YOU'LL BRING
You're the bird we're looking for if you have:
- BA/BS with 5+ or MS with 3+ years' experience in the
biotechnology or pharmaceutical industry
- Experience withmanaging and executing in vivo studies in mice
required, including animal handling, performing routine injections
(sc, ip, iv), tumor measurements, IVIS imaging, necropsy,
collection of blood and tissues
- Experience working with a variety of mouse strains and tumor
models including xenografts, syngeneics, and transgenics
- Experience with PBMC or stem cell engraftments is
- Experience conducting or working alongside research scientists
to analyze tissue samples is desirable
- Experience in maintaining a laboratory notebook and following
- Familiarity with programs such as Excel, Studylog, GraphPad
Prism and PowerPoint for data entry, analysis and
- Excellent organizational skills towards multi-tasking in an
extremely fast-paced environment with changing priorities
All our birds embrace the principles of the bluebird bio
culture: b colorful, b cooperative, b yourself.
bluebird bio is deeply committed to fostering an environment
where diversity and inclusion are not only valued, but prioritized.
We believe a diverse and inclusive community empowers us to act
courageously, care deeply, and dream boldly to impact people in big
ways. Diverse viewpoints bring diverse capabilities which
strengthen our focus and fuel our growth.
bluebird is proud to be an equal opportunity employer, seeking
to create a welcoming and diverse environment. All applicants will
receive consideration for employment without regard to race, color,
religion, gender, gender identity or expression, sexual
orientation, national origin, genetics, disability, age, veteran
status or any other applicable legally protected
Keywords: bluebird bio, Inc., Cambridge , Senior Associate Scientist I/II, In Vivo Pharmacology, Other , Cambridge, Massachusetts
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