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Scientist, Culture Sciences

Company: Rubius Therapeutics, Inc.
Location: Cambridge
Posted on: June 7, 2021

Job Description:

Rubius Therapeutics is a clinical-stage biopharmaceutical company developing a new class of medicines called Red Cell Therapeutics. Our proprietary RED PLATFORM was designed to genetically engineer and culture Red Cell Therapeutics that are selective, potent and off-the-shelf allogeneic cellular therapies for the potential treatment of several diseases across multiple therapeutic areas. Our therapies can potentially be used to kill tumors in cancer and to regulate the immune system for the treatment of autoimmune diseases. We are currently enrolling patients in a Phase 1/2 clinical trial of RTX-240 in patients with relapsed/refractory or locally advanced solid tumors. In addition, RTX-240 is being evaluated in a second Phase 1 arm of the clinical trial for the treatment of patients with relapsed/refractory acute myeloid leukemia, and our IND has been cleared by the U.S. FDA for RTX-321 for the treatment of human papillomavirus 16-positive cancers.

We are proud of our passionate, high-performance culture - one based on a set of values that are the cornerstone of who we are and how we hold ourselves accountable. Founded in 2013, we are headquartered in Cambridge, MA, and our manufacturing facility in Smithfield, RI was named 2020 Top 5 Best Places to Work in Rhode Island among medium-sized companies by Providence Business News. We are currently expanding across all functions within the organization. Red blood cells are no longer just for carrying oxygen. Check us out at www.rubiustx.com, or follow us on Twitter and LinkedIn or like us on Facebook.

Summary

We are looking for a Scientist to join our Culture Science (Rubius Prime) team to design & develop prototypes for our cultured RCT to advance Red Cell Therapeutic prototypes in Discovery. The candidate must be independent, goal oriented, technically competent and able to efficiently work across multiple projects. We are searching for enthusiastic, innovative, and highly motivated individuals, with deep scientific background in cell engineering and engineering processes to mammalian culture systems, who are comfortable working in a fast-paced entrepreneurial environment.

Responsibilities

  • Work closely with Discovery groups to design prototypes across multiple therapeutic groups
  • Work with a team of researchers to guide various scientific projects
  • Develop tools to improve the RCT platform for advancement of various discovery prototypes
  • Utilize strong knowledge of broad scientific and technical concepts and applies this towards assigned projects and department objectives.
  • Independently performs data analysis on complex data sets and/or assignments. Prepares summary reports and proper electronic notebook record keeping.
  • Communication of experimental plans and data to multiple cross-functional scientific teams
  • Support the continued protection, creation, and expansion of company's intellectual property.
  • Assist in maintaining a strong, entrepreneurial and creative culture with a clear sense of urgency and focus on providing transformational therapies to patients.

Qualifications & Education

  • PhD degree in Biochemistry, Bioengineering, Chemical Engineering or related discipline and 2+ years of relevant laboratory experience, pharmaceutical or biotechnology industry preferred
  • Strong background in protein design, protein engineering, cell engineering, and development of methods to improve construct screening
  • Ability to apply deep understanding of the biology involved in cell differentiation for cell engineering.
  • Strong experimental skills and aseptic technique including handling of primary cell culture, mammalian cell lines, molecular biology skills

EEO Statement: Rubius Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & staffing agencies: Rubius Therapeutics does not accept agency resumes unless contacted directly by internal Rubius Talent Acquisition. Please do not forward resumes to our careers@rubiustx.com account, Rubius employees or any other company location; Rubius Therapeutics is not responsible for any fees related to unsolicited resumes.

Keywords: Rubius Therapeutics, Inc., Cambridge , Scientist, Culture Sciences, Other , Cambridge, Massachusetts

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