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Senior Scientist/Principal Scientist - Oncology Drug Discovery

Company: Blueprint Medicines Corporation
Location: Cambridge
Posted on: June 6, 2021

Job Description:

Senior Scientist/Principal Scientist - Oncology Drug Discovery

Cambridge, MA

Requisition Number: BIO21-903

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and hematologic disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for genomically defined cancers, systemic mastocytosis, and cancer immunotherapy.

[Position Objective]


  • Provide broad strategic and technical leadership across programs and initiatives throughout the discovery organization
  • Lead one or more small molecule drug discovery programs in oncology. Provide vision and strategic leadership for the multidisciplinary drug discovery project teams. Manage timelines, milestones, budgets, objectives. Communicate project progress to internal management and external stakeholders.
  • Leverage knowledge of cancer biology to explore the function of oncoproteins in relevant cellular contexts and in vivo models. Work with and coordinate other project team colleagues to translate this knowledge into viable clinical strategies including the molecular definition of potential responders
  • Supervise, mentor and guide the career development of team members
  • Extend and diversify internal capabilities through interaction with CROs as well as external industry and academic collaborators


  • PhD in oncology, cell biology, immunology or related discipline with relevant post-doctoral training
  • 6-8 years of relevant industry experience in a biopharmaceutical setting with extensive experience leading drug discovery project teams from lead optimization to IND-enabling studies
  • Recognized as a leader in the field with a strong publication record in oncology.
  • Strong leadership, interpersonal and communication skills with an enthusiasm for participating in a fast-paced environment characterized by rigorous science and innovative thinking


  • Demonstrated application of expertise to drug discovery in oncology
  • Significant experience leading strong multi-disciplinary teams focused on small molecule drug discovery
  • Familiarity with engaging and managing external efforts with contract research organizations and academic collaborators
  • At home in a results-driven, highly accountable environment where you can make a clear impact
  • A team player and mentor, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Keywords: Blueprint Medicines Corporation, Cambridge , Senior Scientist/Principal Scientist - Oncology Drug Discovery, Other , Cambridge, Massachusetts

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