CambridgeRecruiter Since 2001
the smart solution for Cambridge jobs

Associate Director/Director Discovery Toxicology

Company: Takeda Pharmaceuticals International GmbH
Location: cambridge
Posted on: May 3, 2021

Job Description:

The health and safety of our employees and candidates is very important to us. Due to the current situation related to the Coronavirus (COVID-19), were leveraging our digital capabilities to ensure we can continue to recruit top talent at Takeda. As your application progresses, you may be asked to use one of our digital tools to help you through your recruitment journey. If so, one of our colleagues will explain how these tools will be used during the recruitment process. Thank you.

*Please be aware of an Identity Theft Scheme targeting individuals seeking jobs with Takeda and other employers. See below or here for more info.

Associate Director/Director Discovery Toxicology

Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takedas long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole.

As one of the worlds leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units.

We are a passionate team doing important work that impacts patients lives. If you are driven to create better health and a brighter future, join us!

Success

What makes a successful member of our team? Check out the traits were looking for and see if you have the right mix.

Life at Takeda

A Global Top Employer

Recognized for our culture and way of working, were one of only select companies to receive Top Global Employer status for 2021.

Associate Director/Director Discovery Toxicology

Job ID R0024727 Date posted 04/20/2021 Location Cambridge, Massachusetts

By clicking the Apply button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takedas Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. We endeavor to build an industry-leading Discovery Toxicology program at Takeda. Become a vital contributor to our inspiring, bold mission by joining as a Discovery Toxicologist in our Cambridge, MA office.

Our ideal candidate will have a proven track record in prominent roles supporting cross-functional Discovery teams. She/he is able to leverage their deep insights into cellular and pathway mechanisms, coupled with knowledge of toxicology in order to provide expert advice and direction to improve the quality of therapeutics. An emphasis in the field of Rare Diseases or Immunology as well as experience in gene therapy or oligonucleotide therapy would be a strong plus.

OBJECTIVES

  • As part of the Global Discovery Toxicology Team work in interdisciplinary teams within and across Global Safety to provide safety support to early discovery teams in Rare Diseases and Immuno-oncology and engage in core activities within the Discovery Toxicology group
  • Work as part of a team of safety assessment scientists and more broadly DMPK, pathology, pharmacology, and medicinal chemistry experts to implement discovery toxicology strategy to enable the selection and progression of optimized drug candidates
  • Apply novel toxicity mechanism-based assays and integrated models to support early target safety and chemistry evaluation.
  • Additional responsibilities include leading or supporting inter- and intra-departmental initiatives.

ACCOUNTABILITIES

  • Provide pharmaceutical drug project teams with expert advice and direction to improve the quality of therapeutics selected for further development based on proactive risk assessment of target- and chemotype-related toxicities
  • Develop comprehensive target safety reviews with risk mitigation plan for early drug discovery project teams based on literature, bioinformatics, and other predictive tools.
  • Apply state of the art in silico, in vitro, and in vivo de-risking strategies to aid in the selection and optimization of large and small molecule therapeutics, as well as new therapeutic modalities
  • Lead the development of early hypothesis-driven investigation into mechanisms of toxicity for the proactive management of potential safety liabilities and communication of impact to teams

EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS

  • Minimum of MS/PharmD with 15+ years of pharmaceutical experience or PhD in a scientific discipline and 10+ years of experience working at a pharmaceutical company
  • Demonstrated project team experience at a pharmaceutical company and ability to work effectively in a matrix, global environment as part of a multidisciplinary team
  • Strong problem solver who is highly organized with the ability to thrive in an environment with rapidly changing priorities.
  • Passion to decrease safety related attrition in drug discovery
  • Broad scientific knowledge including pharmacology, toxicology, physiology and biochemistry.
  • Experience in development across mixed modalities, especially oligonucleotides and gene therap and an extensive knowledge in rare diseases, immunology, and/or oncology is desired.
  • Strong interpersonal skills with an ability to develop solid, long term relationships and the ability to influence others, and adept at working across multiple cross-functional areas.
  • Excellent oral and written communication skills
  • DABT certification a plus, but not necessary

This job posting excludes CO applicants

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days

Check out where you could be
working if you apply.

Job Seekers: Protect yourself against identity theft

Please be aware there are instances of identity thieves posting Takeda-branded jobs and posing as employees to steal personal information. They visit job-related websites and invite candidates to online chats. During the chat, they press job seekers to provide bank account information and Social Security numbers.

Copyright 1995-2019 Takeda Pharmaceutical Company Limited. All rights reserved.

Keywords: Takeda Pharmaceuticals International GmbH, Cambridge , Associate Director/Director Discovery Toxicology, Other , cambridge, Massachusetts

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Log In or Create An Account

Get the latest Massachusetts jobs by following @recnetMA on Twitter!

Cambridge RSS job feeds