Stem Cell Research Scientist I
Company: Vertex Pharmaceuticals Inc (US)
Posted on: May 3, 2021
Vertex seeks a talented scientist to join the Vertex Cell and
Genetic Therapies (VCGT) stem cell research group in Boston, MA.
The group’s mission is to discover and actualize the next
generation of cell therapies for diabetes.
We are looking for a candidate with significant experience
leveraging genetic engineering to discover novel stem cell biology,
targeted stem cell differentiation, and/or novel stem cell derived
cell function. The ideal candidate has extensive stem cell and
differentiation (to any lineage) experience and proficiency with
genome editing technologies and theory.
The candidate must be scientifically independent, confident, and
accustomed to taking initiative while problem solving. The position
requires strong communication and organization skills, but also
proven adaptability and multitasking capability.
Design and execute genetic engineering strategies in stem cells,
following through to clone identification, to meet specific goals
within the group.
Characterize edit impact on cell biology with in vitro and in
vivo follow up investigation.
Contribute and pursue novel avenues of cell modification that
may result in improved cell therapies.
Communicate findings and ideas to a broad range of groups within
Perform human pluripotent stem cell culture to support diverse
needs within the group (e.g., various culture formats and
Knowledge and Skills:
Significant pluripotent stem cell culture experience (e.g., hESC
and/or hiPSC). 2D culture experience is required, and 3D is
Experience performing stem cell differentiation to any cell
Proficiency with the theory, design of experiment, and execution
of CRISPR, transposase, TALENS, or other genome modification
approaches to stem cell editing.
Competency with cell-based assays such as flow cytometry, ICC,
glucose stimulated insulin release assays (GSIS), qPCR, ELISA.
Must possess critical thinking and self-reliance to solve tasks
Successful candidate will have outstanding organization and
Candidate must possess flexibility to quickly pivot as projects
The candidate will be accustomed to effectively communicating
progress, needs, and problems.
Preferred Education and
Keywords: Vertex Pharmaceuticals Inc (US), Cambridge , Stem Cell Research Scientist I, Other , Cambridge, Massachusetts
Didn't find what you're looking for? Search again!