Associate Scientist II, Cellular Process Development

Company: bluebird bio
Location: Cambridge
Posted on: April 8, 2021

Job Description:

Associate Scientist II, Cellular Process Development On January 11, 2021, we announced our intent to separate our severe genetic disease and oncology businesses into differentiated and independent publicly traded companies. We will retain focus on severe genetic disease (SGD) and will launch our oncology business ("Oncology Newco") as a new entity, with the completed transition expected by the end of 2021. ABOUT THE NEST At bluebird, only two things matter - patients and our people. When you join the nest, you're not just landing a new gig, you become a part of a flock that's soaring to new heights. We're 1100+ doers, thinkers and collaborators across the globe with a strong sense of our values and our purpose. Our innovation and sustainability are rooted in the diversity of our teams and results are achieved through cooperation and the incorporation of multiple points of view. This is personal and we approach every challenge with radical care. The time is now to rise up and recode the science, the systems, and the status quo. ABOUT THE FLOCK The Cellular Process Development team for Sickle Cell Disease is all about designing processes to manufacture high quality stem cells in an innovative and scalable way for our patients. We develop the gene therapy manufacturing platform and chaperone it from pre-clinical to commercial manufacturing phases in collaboration with other teams across Pharmaceutical Sciences, Research and Clinical. With one approved product (Zynteglo---) and multiple clinical stage candidates, there is a wealth of growth opportunities for driven scientists to make a significant impact in the lives of patients. Come join our incredibly talented team of birds and learn more about how you can drive scientific advancements that ultimately serve patients with gene-modified stem cell products! The focus of this position is to work on determining functional understanding and characterization of drug product manufacturing processes for stem cell therapies. We are looking for a motivated associate scientist to drive development and characterization projects. HOW YOU'LL FLY As an Associate Scientist bird reporting to a Scientist, you'll help to bring more patients their bluebird days by:

• Performing experiments involving the isolation, transduction, expansion, and cryopreservation of gene-modified cells for treatment severe genetic diseases
• Executing complex technical work related to stem cell biology, including cell isolation, viral gene transfer, tissue culture, PCR, flow cytometry, and other immunological assays
• Working with all aspects of mammalian cell culture, including media and buffer preparation, culture initiation, propagation, and cryopreservation of cells, including primary human cells
• Successfully completing general laboratory tasks including equipment maintenance
• Maintaining accurate and reliable record keeping including database management, batch records, notebooks, and all other pertinent documentation
• Executing hands-on lab work with a flexible schedule based on experimental work (some weekend work may be needed) WHAT YOU'LL BRING You're the bird we're looking for if you have:
  • BS in cell biology, immunology, biochemical engineering, or related with 2+ years of experience in a GMP/GLP environment
  • Mammalian and primary cell culture experience (required)
  • Working knowledge of a variety of cell-based methods
  • Strong understanding of tissue culture, cell biology, immunoassays, and general laboratory techniques
  • Experience in engineering with scaling design of primary cell-based bioreactors
  • Experience with hematopoietic stem cells (preferred) All our birds embrace the principles of the bluebird bio culture: b colorful, b cooperative, b yourself. bluebird bio is deeply committed to fostering an environment where diversity and inclusion are not only valued, but prioritized. We believe a diverse and inclusive community empowers us to act courageously, care deeply, and dream boldly to impact people in big ways. Diverse viewpoints bring diverse capabilities which strengthen our focus and fuel our growth. bluebird is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics. Will you now or in the future require bluebird bio to commence ("sponsor") an immigration case in order to employ you (for example, H-1B or other employment-based immigration case)? --*
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Keywords: bluebird bio, Cambridge , Associate Scientist II, Cellular Process Development, Other , Cambridge, Massachusetts