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Senior Scientist, Analytical Development (Chromatography

Company: Intellia Therapeutics, Inc.
Location: Cambridge
Posted on: April 9, 2021

Job Description:

Senior Scientist, Analytical Development (Chromatography) Why Join Intellia?-- Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just "treat" people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together. How You Will Achieve More with Intellia Be the next Senior Scientist to join our Analytical Development team! In this role, you will be will lead the development and execution of studies to characterize Intellia's candidates by chromatography and Biophysical methods to support product characterization, formulation development, process development, and manufacturing. In this opportunity, your main responsibilities will include: Functions independently as technical expert in chromatography method development, execution and troubleshooting including but not limited to (HPLC, RP-HPLC, IEX-HPLC, CE-SDS, cIEF (R, NR) AUC, DLS Knowledge of Sanger Sequencing highly desired Strong knowledge of analytical methods for cell and gene therapy products is required. Plans and reviews own weekly/monthly activities for team with input in accordance with group/lab objectives and priorities, Perform routine analytical testing in support of process development in process activities in house and product characterization Support the development of new methods by identifying, evaluating, and executing analytical methods to support ongoing analytical needs Participate in the support of analytical activities at CMOs and CTOs related to analytics including method qualification and validation, data trending, troubleshooting, optimization, review and reporting Assist in the execution of analytical development activities at CTOs and CMOs, including deliverables and timelines; participate in tech transfer of intellectual property, protocols/procedures and know-how from internal labs to QC and CMOs/CTOs, or between CMOs/CTOs Participate in BLA-enabling activities including product and process characterization, comparability studies, CQA assessment activities Assist in review and writing of regulatory filings including IND/IMPD and BLA Collaborate with process development, QA and QC functions to ensure strong cross functional collaborations and integrated process and product development and characterization About you Ph.D. in chemistry, biology, biochemistry or related field and 4+ years of experience or Masters' degree and 6+ years' experience in analytical development within a biotech/pharmaceutical analytical development and/or Quality Control environment required Must have experience with Gene therapy or related fields Theoretical and hands-on knowledge and experience with chromatography and biophysical methods used for biopharmaceutical characterization and routine testing and impurity identification The team is currently working mostly onsite to execute workflows in a wet - lab environm ent. Therefore, we strongly prefer the candidate to be currently local to Cambridge MA, or open to relocating. If you join our team, you can expect to join a hardworking and collaborative environment. We look forward to fostering your skills, learning from your experiences, and building a larger team that will make a difference in patient's lives. EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. In the next window you will be prompted to create a candidate account. You can log into your candidate account anytime to view the status of your job application(s). Intellia Therapeutics and the Intellia Therapeutics logo are registered trademarks with the U.S. Patent & Trademark Office.

Keywords: Intellia Therapeutics, Inc., Cambridge , Senior Scientist, Analytical Development (Chromatography, Other , Cambridge, Massachusetts

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