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Principal Scientist

Company: THIRD ROCK VENTURES, LLC
Location: Cambridge
Posted on: April 8, 2021

Job Description:

Computational Biology, Principal Scientist at MOMA Therapeutics At MOMA Therapeutics, we are discovering the next generation of medicines. We are motivated by a single common goal, to discover and develop innovative new medicines for patients through our singular focus: the therapeutic targeting of molecular machines. Imagine joining a company where you---.--

  • Will be part of an experienced and resilient team that is collectively unstoppable, trusts one another, and selflessly collaborates--
  • Will work with incredible colleagues who are committed to the collective discovery of transformative medicines for patients
  • Are needed---because the work you will do--has strategic impact--and because patients are counting on you In this role you will:--
    • Drive the computational biology capability across the discovery organization. This critical and dynamic role requires an exceptional ability to generate, interrogate and refine biological hypotheses using large-scale genomic data--
    • Collaborate with--lab--scientists and teams across the organization to--generate--actionable and impactful--patient responder hypotheses--that can be tested in the lab or the clinic--
    • Creatively integrate internal and external large-scale datasets to generate unique disease insights that directly impact drug discovery projects--
    • Regularly present scientific--hypotheses and--findings to scientific leadership teams-- About you:--
      • You have completed a--post-doc and have extensive computational biology experience in academia or the pharmaceutical/biotech industry--
      • You have a PhD in computational biology, oncology, cell biology,--genetics, or a similar computational/biology--related--field--
      • You have proven experience in effectively--working with lab scientists to--formulate--and answer biological questions through the computational integration and analysis of data--
      • You're an expert--in--current and emerging public genomic/proteomic databases (e.g. TCGA,--DepMap,--gnomAD,--UK Biobank, Project Score...)--
      • You have a solid understanding of statistical/algorithmic principles--behind common genomics approaches--
      • Fluent in R--and in one or more additional programming languages (e.g.--Python,--Julia, Rust)--
      • You are comfortable working in multiple computing environments including cloud-based platforms
      • You--understand and value--reproducible data analysis approaches (e.g.--using--Jupyter/Rmd--notebooks, version tracking through git,--designing/executing--nextflow--workflows)--
      • You work hard, you are kind to others, and you enjoy being a part of a collaborative team that--delivers 29 Newbury Street
        3rd Floor
        Boston, MA 02116
        P (617) 585-2000

Keywords: THIRD ROCK VENTURES, LLC, Cambridge , Principal Scientist, Other , Cambridge, Massachusetts

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