Global Lead, Next Generation Sequencing

Company: Novartis
Location: Cambridge
Posted on: April 5, 2021

Job Description:

1 Purpose. To reimagine medicine.

The Chemical Biology and Therapeutics (CBT) department merges ground breaking technical capabilities with deep scientific expertise to deliver bold innovations at the forefront of science. As the Global Lead of the Next Generation Sequencing team in CBT, you will spearhead our efforts to drive innovation through the development and deployment of new genomic methods allowing rapid discovery of new biology, novel drug targets, and disease biomarkers. You will lead a global team of wet bench and in silico scientists, promoting emerging genomic technologies and related bioinformatic approaches in our organization and beyond.

Your Responsibilities Include:

- Maintain and advance our suite of next-generation sequencing methodologies including RNA-seq, ChIP-seq, single cell RNA-seq, spatial transcriptomics, long read sequencing, etc. Proactively identify new genomic solutions and develop a strategy for their implementation based upon the emerging needs across the NIBR organization.

- Engage with Disease Area and genomic specialists across the community.

- Partner with NIBR Data Scientists to ensure maximum impact, invest in data as a key asset, and help define data analysis standards. Drive the identification and use and/or development of innovative analytical methods based on technology needs.

- Be responsible for the outsourcing of genomics assays to external vendors for regular activities, ensure that research study timelines for data delivery are met, and that the data meets high quality standards as well as regulatory and legal requirements.

- Build and implement a governance structure to ensure a science-driven prioritization strategy, and ensure timely and transparent communication to stakeholders

- Establish effective relationships with cross functional scientific teams in a matrixed environment, and ensure alignment of plans and strategies with NIBR leadership team and Disease Area heads.

- Partner with external innovators, academics, biotechs, and other Pharmas to identify/evaluate new technologies and outstanding biology research

- Lead cross-departmental teams, department-wide initiatives, and work streams.

- Publish internally and externally as the main contributor, to improve Novartis and CBT/Genomic Sciences visibility.

EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. What You'll Bring to the Role:

- Knowledge of genomics applications in multiple disease areas and ability to articulate questions which can be answered from sophisticated data sets.

- A robust understanding of the drug discovery process, from exploratory to clinical stages, and across numerous therapeutic modalities including small molecule, biologics, and cell and gene therapy.

- An enterprise-wide mentality with demonstrated ability to prioritize projects across a large matrix organization and a strong focus on delivering high impact science for key NIBR projects.

- A track record of developing talent and leading teams by crafting and supporting a Curious, Inspired, and Unbossed culture.

- A strong publication record demonstrating a focus on advancing genomics technology in support of complex disease biology

Desirable Requirements:

- PhD in biology, genomics, computational biology or a related field, with 10+ years of demonstrated ability in multiple genomics technologies and applications.

- Extensive supervisory experience of both wet lab and in silico teams engaged in groundbreaking genomics research.

Why Consider Novartis?

799 million. That's how many lives our products touched in 2019. And while we're proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people's lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you're given opportunities to explore the power of digital and data. Where you're empowered to risk failure by taking smart risks, and where you're surrounded by people who share your determination to tackle the world's toughest medical challenges.

Imagine What You Could do at Novartis!

Commitment to Diversity and Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Novartis, Cambridge , Global Lead, Next Generation Sequencing, Other , Cambridge, Massachusetts