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Scientist/Senior Scientist, Computational Biology

Company: Nomis Solutions
Location: Cambridge
Posted on: April 5, 2021

Job Description:

Scientist/Senior Scientist, Computational Biology Beam is seeking an innovative and collaborative computational scientist to support the development of novel gene editing therapies using our next-generation, state-of-the-art technology. The individual in this position will play a key role in developing Beam's computational biology tools and infrastructure and will work closely with experimental scientists to support therapeutic programs and other research activities. Primary Responsibilities:

  • Develop computational pipelines to analyze data from novel and existing next-generation sequencing (NGS) assays for the assessment of on-target and potential off-target gene editing events
  • Analyze complex biological datasets by deploying statistical methods and visualization tools to draw conclusions
  • Work closely with program teams and provide computational support for target identification, guide RNA design, experimental design, and follow-up data analysis such as targeted genome sequencing and RNA sequencing.
  • Create and implement computational tools to support gene editing and other research activities to facilitate data interpretation and sharing
  • Collaborate with software and cloud engineers to build production-scale pipelines
  • Communicate scientifically rigorous findings via verbal and written communications, visualizations, and presentations Qualifications:
    • A Ph.D. or MS in Bioinformatics, Computational Biology, Computer Science, Statistics, or equivalent field
    • Industry experience is preferred
    • Strong scientific background, including an understanding of molecular biology and genomics
    • Publication record in computational biology
    • Knowledge of relevant programming languages, such as Python, R, and/or Java
    • Familiarity with common bioinformatics tools for NGS data analysis and working with "omics" datasets
    • Experience with AWS or similar cloud computing platform
    • Ability to work independently while also building relationships with colleagues U.S. Equal Opportunity Employment Information (Completion is voluntary) Individuals seeking employment at Beam Therapeutics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. You are being given the opportunity to provide the following information in order to help us comply with federal and state Equal Employment Opportunity/Affirmative Action record keeping, reporting, and other legal requirements. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. Gender Please select Are you Hispanic/Latino? Please select Race & Ethnicity Definitions If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985. Veteran Status Please select Form CC-305 OMB Control Number 1250-0005 Expires 05/31/2023 Voluntary Self-Identification of DisabilityWhy are you being asked to complete this form? We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years. Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp . How do you know if you have a disability? You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition. Disabilities include, but are not limited to:
      • Autism
      • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
      • Blind or low vision
      • Cancer
      • Cardiovascular or heart disease
      • Celiac disease
      • Cerebral palsy
      • Deaf or hard of hearing
      • Depression or anxiety
      • Diabetes
      • Epilepsy
      • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
      • Intellectual disability
      • Missing limbs or partially missing limbs
      • Nervous system condition for example, migraine headaches, Parkinson's disease, or Multiple sclerosis (MS)
      • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression Disability Status Please select 1 Section 503 of the Rehabilitation Act of 1973, as amended. For more information about this form or the equal employment obligations of Federal contractors, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp . PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Keywords: Nomis Solutions, Cambridge , Scientist/Senior Scientist, Computational Biology, Other , Cambridge, Massachusetts

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