CambridgeRecruiter Since 2001
the smart solution for Cambridge jobs

Senior Associate Scientist, Pharmacology

Company: Pfizer
Location: Cambridge
Posted on: April 5, 2021

Job Description:

**ROLE SUMMARY** The Internal Medicine Research Unit (IMRU) is seeking a highly motivated laboratory scientist to be a member of the GPCR pharmacology group. This Senior Associate Scientist will be an integral member of a team which broadly supports the IMRU portfolio across various disease areas. The individual will apply his in vitro pharmacology expertise to develop assays and design experiments to define the structure-activity relationships and understand the mechanism of action of compounds throughout different stages of the projects. In this position, the successful candidate will be collaborating with multiple groups including discovery biology, medicinal chemistry and primary pharmacology. **ROLE RESPONSIBILITIES** + Primary focus will be the conduct of cell and tissue-based studies to generate in-depth pharmacology knowledge of compound mechanism of action and relevance to human biology. + Individual is expected to understand relevant scientific literature and develop technical competencies in the area of in vitro and ex vivo GPCR and cytokine receptor pharmacology. + Candidate will perform experiments, establish robust biochemical/ cell-based screening assays, analyze/ summarize data, and communicate results with the project team. + Maintain immortalized and primary cell cultures as needed for assay development and screening efforts. + Collaborate with the Primary Pharmacology Group to ensure alignment around assay technology selection, assay quality criteria and validation requirements. + Prepare and present experimental results to project teams + Maintain high quality experimental records within electronic laboratory notebook. **BASIC QUALIFICATIONS** + Bachelors or Masters degree in biology, pharmacology, biochemistry or a related field with at least 3 years of relevant lab experience. **PREFERRED QUALIFICATIONS** + Prior experience or expertise in GPCR pharmacology. + Knowledge of traditional second messenger signaling assays as well as cutting-edge approaches to dissect GPCR function including FRET-based binding assays, BRET-based signaling biosensors, label-free technologies, etc. + Molecular and cell biology experience including cell culture (primary and immortalized), gene silencing and expression analyses. + Good organization skills with high level of initiative in performing and troubleshooting experiments. + Comfort with relevant software tools such as Microsoft Excel and GraphPad Prism is preferred. + Experience in low to moderate throughput compound screening preferred but not mandatory. + Ability to multitask, work on multiple projects and be an integral member of cross-functional project teams. + Proven verbal and written communication skills and present results in individual and group settings. + The successful candidate will be an enthusiastic quick learner excited by a role with high demands. **Other Job Details:** + **Last Date to Apply for Job: March 22, 2021** + Eligible for Relocation Package: YES + Eligible for Employee Referral Bonus: YES **\#LI-PFE** **Sunshine Act** Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. **EEO & Employment Eligibility** Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. Research and Development \#LI-PFE

Keywords: Pfizer, Cambridge , Senior Associate Scientist, Pharmacology, Other , Cambridge, Massachusetts

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Other Jobs


Front of Store Attendant
Description: Front of Store Attendant 387603878 Taunton, Massachusetts, US, 02780 Lot Associates assist customers with
Company: The Home Depot
Location: Taunton
Posted on: 04/12/2021

CDL-A Company Driver - OTR Dry Van - Graduated Training (Concord,NH)
Description: Hiring: CDL-A Drivers for OTR Company Driving Positions. 5000 Sign on Bonus
Company: Big M Diesel Express
Location: Concord
Posted on: 04/12/2021

Aviation Rescue Swimmer
Description: RESPONSIBILITIES br br As an AIRR, you must be prepared to enter the most treacherous conditions to provide recovery and relief for rescue missions, humanitarian assistance and operational support. (more...)
Company: Navy
Location: Taunton
Posted on: 04/12/2021


Navy Diver
Description: ABOUT br br Their accomplishments are epic. Their expertise is unrivaled. No other force is more intensely trained to succeed in the perilous world of underwater adventure. Each assignment they take (more...)
Company: Navy
Location: East Providence
Posted on: 04/12/2021

Residential Counselor
Description: Bay State Community Services br NEW PAY RATES AVAILABLE W/ 1000 Sign On Bonus br Programs located in Plymouth and Weymouth - 16.50 per hour br br The Residential Counselor (more...)
Company: Bay State Community Services
Location: Weymouth
Posted on: 04/12/2021

Magnetic Lap
Description: Description:Must Haves1 year of manufacturing experienceThe candidate will have to work off a daily work order to polish parts. Minor sandblasting basic inspection with micrometers and visuals. Will cross-train (more...)
Company: Aerotek
Location: East Providence
Posted on: 04/12/2021

Drive with Gopuff
Description: Gopuff , a leading consumer technology platform delivering everyday essentials in minutes from local facilities, is looking for delivery partners to deliver through goDrive , an app that connects Delivery (more...)
Company: Gopuff
Location: East Providence
Posted on: 04/12/2021

Sr. Associate, Credit Risk (Auto)
Description: The Sr. Associate, Credit Risk is responsible for partnering with the accountable business owner within 1st line of defense Risk Management and Controls. S/he is responsible for the remediation of the (more...)
Company: Santander Holdings USA Inc
Location: East Providence
Posted on: 04/12/2021

Front of Store Attendant
Description: Job DescriptionLot Associates assist customers with the loading of their vehicles and also monitor
Company: The Home Depot
Location: Taunton
Posted on: 04/12/2021

Store Associate
Description: Store Associate 387659847 Concord, New Hampshire, US, 03301 Lot Associates assist customers with the loading
Company: The Home Depot
Location: Concord
Posted on: 04/12/2021

Log In or Create An Account

Get the latest Massachusetts jobs by following @recnetMA on Twitter!

Cambridge RSS job feeds