Senior Associate Scientist, Analytical Development in Cambridge, MA US at Apex Systems

Company: Apex Systems Inc.
Location: Cambridge
Posted on: February 23, 2021

Job Description:

• Senior Associate Scientist, Analytical Development Senior Associate Scientist, Analytical Development in Cambridge, MA US at Apex Systems Scientist, Analytical Development 1121806 Job Scope & Purpose: Our Cambridge based client is looking for a talented Scientist in Analytical Development to join their team. The qualified candidate will have a background in analytical development, as well as good hands on experience with flow cytometry, cell culture and cell based assays. If you are ready to join our growing client, please apply! Primary Job Responsibilities:
  • Apply your expertise in developing and qualifying analytical assays to support the release and characterization of viral vector and cell therapy products in early and later phases of development
  • Design, plan, and execute experiments in Analytical Development, working both independently and as part of a multidisciplinary team of researchers
  • Support development and/or improvement of methods in collaboration with research and vector process development to characterize viral vector production methods and primary cell transduction (eg T cell, TIL, NK cell)
  • Support the introduction of new analytical technologies, implementation of common reagents and controls, trending of data, and protocols to support construct screening, research studies, research vector production, and CDMO tech transfer activities
  • Interpret results, troubleshoot technical hurdles, and propose solutions to the team
  • Maintain excellent records of experiments, including Electronic Notebook entries, authoring of protocols, test methods, and study reports
  • Collaborate effectively across--organization, present internally to project teams, management, and scientific teams Primary Job Requirements:
    • BS or MS in a relevant discipline (molecular biology, cell biology, biomolecular engineering, biotechnology or relevant field)
    • Minimum of 6-10 years relevant industry experience including prior direct experience with analysis of viral vectors and/or cell therapies
    • Demonstrated track record with analytical techniques focused on cell biology, immunology, molecular biology, and potency assay development
    • Subject matter expertise in analytical development, including methods such as cell line/ primary cell transduction/ transfection, multicolor flow cytometry/ FACS, qPCR/ ddPCR, ELISA, MSD, and western blot
    • Strong troubleshooting and communication skills, highly organized with strong record-keeping and an ability to multi-task
    • Highly collaborative working style and ability to adapt in a fast-paced, rapidly developing environment
    • Ability to work with general direction to meet objectives and timelines, adapting to changes and priorities in order to fulfill our mission Additional Bonus Requirements:
      • Experience with development of flow cytometry-based assays for release and characterization
      • Experience in analytical development supporting early and/ or late-stage development of biologics is highly desirable (cell therapy, gene therapy, vaccines, antibodies)
      • Demonstrated track record with analytical development and method qualification for characterization of engineered cell therapies
      • Familiarity with viral vector production and cell line engineering
      • Experience with Design of Experiment (DOE) approaches and application to analytical development
      • Experience working with CDMOs/ CTLs for method transfer/ development/ qualification/ validation
      • Familiarity with FDA and EMA guidance documents relevant to gene and cell therapy analytical development and method validation About Stratacuity: Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
        PROVEN SCIENTIFIC PLACEMENT--- Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us. dhagenbuch@stratacuity.com Code: DiscDevt EEO Employer Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystemsinc.com or 844-463-6178. Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystems.com (Do not submit resumes or solicit consultants to this email address) or 844-463-6178. Join our Talent Network!

Keywords: Apex Systems Inc., Cambridge , Senior Associate Scientist, Analytical Development in Cambridge, MA US at Apex Systems, Other , Cambridge, Massachusetts