Senior Principal Scientist, Medicinal Chemistry and Molecular Design
Company: Black Enterprise Magazine
Location: Cambridge
Posted on: January 14, 2021
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Job Description:
Senior Principal Scientist, Medicinal Chemistry and Molecular
Design **Would you like to discover the medicines of the
future?**
At Pfizer we deliver Breakthroughs That Change Patients Lives . In
the Medicine Design group we play a vital role in this mission
through the discovery of Pfizer's small molecule and
synthetically-derived drugs. We are seeking leaders in Medicinal
Chemistry to join our world-class Medicine Design team in Cambridge
MA to build upon our rich history of innovation in Medicinal
Chemistry and Molecular Design and deliver Pfizer's drugs of the
future.
Discovering new medicines at Pfizer takes teams with a diversity of
skills, behaviors and approaches. Creativity, scientific
excellence, tenacity, passion, hard work, organization, teamwork,
courage, open-mindedness, curiosity - are just some of the traits
successful Drug Discovers display at Pfizer, and we are looking for
ambitious Medicinal Chemists, eager to see their work lead to
important new medicines and scientific breakthroughs, to join our
team.
The Medicine Design group in Pfizer comprises experts in the major
scientific disciplines involved in the discovery and preclinical
development of small molecule drugs: molecular design, synthesis,
computational chemistry, pharmacology, chemical biology, structural
biology, biophysics, DMPK and analytical chemistry. We have long
been renowned not only for delivering high quality drug candidates
into the clinic but also for establishing new drug design
approaches and principles, such as the "Rule of 5" and
property-based drug design, that have raised the bar of quality in
the discipline and been widely-adopted across the industry.
As a Senior Principal Scientist in Medicinal Chemistry and
Molecular Design at Pfizer you will play a vital role as leader or
key contributor of a large, multi-disciplinary matrix teams from
project inception through to delivery of clinical drug candidates.
You will also lead or provide key contributions to teams of
scientists looking to combine Pfizer's expertise and large-scale
research investments, with external academic and biotech
collaborations, to revolutionize our approach to the discovery and
development of small molecule and synthetically-derived drugs.
**Role Responsibilities**
+ Accountable for driving a strong scientific agenda and the
application of expert data analysis and contemporary design tools
to drive effective target design and prioritization within a
portfolio of projects
+ Contribute to medicinal chemistry strategy and devising hit ID
strategies to move projects through the Hit-to-Lead phase with
scientific excellence, efficiency and speed
+ Partner with enabling functions within Medicine Design to lead
projects through the Lead Optimization phase, ensuring the delivery
of small molecule/synthetic drug candidates with scientific
excellence, efficiency and speed
+ Contribute to the identification of new small molecule projects
to the portfolio through collaborations with disease area
biologists
+ Influence innovation and excellence in Medicinal Chemistry
through advocating novel approaches, methods and modalities to the
drug discovery process
+ Play a key role in enhancing the external reputation of Pfizer's
Medicinal Chemistry, Molecular Design and synthetic Drug Discovery
capabilities through high profile publications and presentations at
leading conferences
+ Work with local leadership to put in place an active program of
self-development in medicinal chemistry and molecular design
skills
**Qualifications**
**Basic Qualifications**
+ Doctorate level degree in relevant area of science, or equivalent
industrial experience
+ Minimum 5 years of relevant experience in the Pharmaceutical
Industry
+ Track record of delivering high impact contributions to Med Chem
projects
+ Expert working knowledge of the key Medicinal Chemistry concepts
and design tools required for pharmaceutical drug discovery
+ Consistent record of peer-reviewed publications from scientific
work to date, to include medicinal chemistry/ drug discovery
**Preferred Qualifications**
+ Examples of high impact publications in Medicinal Chemistry/ Drug
Discovery
+ Experience of playing a leading role in matrixed teams of
internal/CRO scientists to deliver project objectives
+ Demonstrated learning agility and success moving into and
mastering new or unfamiliar areas of science.
**Along with a Resume/CV, please include a short research summary
of your relevant research.**
**Other Job Details:**
+ Eligible for Relocation Package
+ Eligible for Employee Referral Bonus
+ \#LI-PFE
**Sunshine Act**
Pfizer reports payments and other transfers of value to health care
providers as required by federal and state transparency laws and
implementing regulations. These laws and regulations require Pfizer
to provide government agencies with information such as a health
care provider's name, address and the type of payments or other
value received, generally for public disclosure. Subject to further
legal review and statutory or regulatory clarification, which
Pfizer intends to pursue, reimbursement of recruiting expenses for
licensed physicians may constitute a reportable transfer of value
under the federal transparency law commonly known as the Sunshine
Act. Therefore, if you are a licensed physician who incurs
recruiting expenses as a result of interviewing with Pfizer that we
pay or reimburse, your name, address and the amount of payments
made currently will be reported to the government. If you have
questions regarding this matter, please do not hesitate to contact
your Talent Acquisition representative.
**EEO & Employment Eligibility**
Pfizer is committed to equal opportunity in the terms and
conditions of employment for all employees and job applicants
without regard to race, color, religion, sex, sexual orientation,
age, gender identity or gender expression, national origin,
disability or veteran status. Pfizer also complies with all
applicable national, state and local laws governing
nondiscrimination in employment as well as work authorization and
employment eligibility verification requirements of the Immigration
and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Research and Development
Keywords: Black Enterprise Magazine, Cambridge , Senior Principal Scientist, Medicinal Chemistry and Molecular Design, Other , Cambridge, Massachusetts
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