CambridgeRecruiter Since 2001
the smart solution for Cambridge jobs

Principal Research Scientist I/II, Neuroinflammation Drug Discovery

Company: AbbVie, Inc.
Location: Cambridge
Posted on: January 13, 2021

Job Description:

Principal Research Scientist I/II, Neuroinflammation Drug Discovery

  • Cambridge, United States of America
  • Research and Development
  • 2009220 Job Description About AbbVie
    AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

    AbbVie's Foundational Neuroscience Center (FNC) in Cambridge, Massachusetts aims to discover breakthrough treatments for Alzheimer's, Parkinson's, and other neurodegenerative diseases, by conducting in-depth research into fundamental pathological mechanisms, and targeting those mechanisms with world-leading small molecule and biologic drug discovery capabilities. The neuroinflammation group seeks an experienced scientist to conduct and lead target validation and drug discovery projects at its Cambridge, Massachusetts site. Our mission is to produce novel drug candidates that modulate microglial biology in neurodegenerative diseases by targeting mechanisms that emerge from in house-generated single cell transcriptional profiling data and other insights. The successful candidate will bring a deep understanding of mechanisms of neuroinflammation, particularly microglial biology, and a strong record of accomplishment in drug discovery research, in a multidisciplinary environment. This is a "hands on" position with both leadership and bench research responsibilities.
    --
    Key Responsibilities
    • Lead and contribute to target identification and validation research, specifically in the role of neuroinflammation in neurodegenerative diseases. Lead and contribute to drug discovery and advancement research.
    • Stay abreast of, and contribute to, relevant literature.
    • Conduct and oversee the design, execution, and interpretation of novel bench research.
    • Collaborate with colleagues at multiple AbbVie sites to identify and optimize drug leads to produce clinical candidates of outstanding promise.
      Qualifications
      Qualifications:
      • PhD in Neuroscience or related field, with typically 6 - 8+ years of experience, including industrial drug discovery;--or Master's Degree or equivalent with typically 12 - 14+ years of experience; or Bachelor's Degree or equivalent with typically 14 - 16+ years of experience
      • Significant accomplishments in neuroinflammation research and neurodegenerative disease drug discovery, with a strong record of publications and patents
      • Expertise in neuroinflammation and microglial biology
      • Expertise in relevant technologies, such as microglia or hematopoetic iPSC cell culture; genomics, transcriptomics, or proteomics; RNAi or CRISPR screening; flow cytometry; and high content phenotypic screening. Interest in advancing rapidly developing technologies, track record of developing innovative model systems
      • Experience in working in multidisciplinary teams, and in external collaboration
      • Alzheimer's and/or Parkinson's disease experience
        Significant Work Activities
        N/A
        Travel
        Yes, 5 % of the Time
        Job Type
        Experienced
        Schedule
        Full-time
        Job Level Code
        M
        Equal Employment Opportunity
        At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
        As an online job seeker, you could be a target of cyber (online) thieves seeking to secure personal information from you by sending you "phishing" messages. Please be alert to and protect yourself from phishing scams. Click here to find out how you can avoid being a victim of job phishing scams.

Keywords: AbbVie, Inc., Cambridge , Principal Research Scientist I/II, Neuroinflammation Drug Discovery, Other , Cambridge, Massachusetts

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Other Jobs


Process Development Associate , Vectors
Description: Process Development Scientist Downstream, Bioprocess, Viral Vectors, AAV 305174 br br RESPONSIBILITIES: br br br Bioprocess br Downstream Process Development, process optimization for (more...)
Company: Yoh, A Day & Zimmermann Company
Location: Medford
Posted on: 01/24/2021

Direct Care Staff, Residential Programs
Description: Fidelity House CRC provides community residences and supportive services for over 1200 individuals who face a wide range of intellectual disabilities such as cerebral palsy, Down Syndrome, combined cognitive (more...)
Company: Fidelity House CRC
Location: Methuen
Posted on: 01/24/2021

Process Development Associate , Vectors
Description: Process Development Scientist Downstream, Bioprocess, Viral Vectors, AAV 305174 br br RESPONSIBILITIES: br br br Bioprocess br Downstream Process Development, process optimization for (more...)
Company: Yoh, A Day & Zimmermann Company
Location: Brookline
Posted on: 01/24/2021


Benevis: Endodontist
Description: Job DescriptionMulti-location
Company: Benevis
Location: Chelsea
Posted on: 01/24/2021

In-Home Care Companion
Description: We are hiring caregivers for all kinds of in home positions near you We make sure that all caregivers on our care team are given every available resource so that you truly enjoy the work you do everyday (more...)
Company: CareInHomes
Location: Weymouth
Posted on: 01/24/2021

MD / Family Practice Job in Salem, Massachusetts / Permanent
Description: Physician / Family Practice / Salem, MA br br FP Physician needed in
Company: Murdock Consulting
Location: Salem
Posted on: 01/24/2021

High Demand For Quality Handymen - Get New Clients In Your Area
Description: Over 25 million homeowners have trusted HomeAdvisor 1800Contractor to help them find quality professionals with the expertise to turn their home improvement
Company: HomeAdvisor
Location: Concord
Posted on: 01/24/2021

Sr Staff Supervisor Manufacturing
Description: br Part of your life. Part of tomorrow. br br We make life easier, safer and greener - with technology that achieves more, consumes less and is accessible to everyone. Microelectronics from Infineon (more...)
Company: Infineon Technologies Americas Corp.
Location: Leominster
Posted on: 01/24/2021

Part Time Teller, Lynn
Description: Job Description Part Time Teller, Lynn, MA - 2100239 Description As a member of
Company: Santander
Location: Chelsea
Posted on: 01/24/2021

Virtual Career Fair / Open Interviews ALL Positions - Plymouth
Description: We're hosting a VIRTUAL hiring event for our Plymouth location on Friday, January 22nd from 9:00am - 5:00pm All you have to do is apply now --Accelerate your potential. Interested in a rewarding career (more...)
Company: Valvoline Instant Oil Change
Location: Plymouth
Posted on: 01/24/2021

Log In or Create An Account

Get the latest Massachusetts jobs by following @recnetMA on Twitter!

Cambridge RSS job feeds