Statistician III
Company: Unicon Pharma
Location: Cambridge
Posted on: January 11, 2021
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Job Description:
Job Description: Looking for a motivated and experienced
statistician with a solid background in nonclinical statistics,
strong consulting skills, and an interest in collaborating with
research scientists in drug discovery and development. He/She will
work closely with research scientists seeking to Client new
medicines in a variety of therapeutic areas by supporting the
design and analysis of preclinical experiments covering all aspects
of drug discovery from disease target identification, pharmacology
studies, animal model development, biomarker development and
demonstration of proof of concept. The focus will be on both
"platform" approaches (ie ensuring robust assay methods) as well as
specific project approaches. The ideal candidate will have a
genuine interest in understanding drug target biology in order to
provide effective statistical consultation with biological
scientists. Responsibilities: Collaborate with preclinical
scientists across research units (Immunology & Inflammation,
Internal Medicine, Rare Disease, CTI) to design, analyze and
present experiments. Bring innovative statistical thinking and
methods to help drive the enhanced quantitative drug discovery and
development paradigm within Pharmaceutical. Ensure rigorous
approaches are taken to ensure good scientific practices are
followed: excellent statistical methods utilized and documented in
protocols, analysis plans and manuscripts, and assay methods are
appropriately blinded, randomized and designed to meet clear
objectives. Serve as a core member of scientific teams responsible
for determining strategy and delivering results in a timely and
high quality manner. Work with scientists to understand the biology
and improve existing biomarkers, endpoints, derive new endpoints,
and develop 'fit-for-purpose' statistical models. Use statistical
expertise to prepare both internal and external reports,
presentations and manuscripts, with the aim to improve the quality
of internal decision making and increase our influence on the
external environment. Where possible, standardize processes and
methodologies within and possibly across therapeutic areas may
include developing statistical tools to aid scientists in
standardize analyses. Provide statistical expertise on regulatory
submissions and ensure quality of deliverables. Qualifications: PhD
in Statistics/Biostatistics and at least 3-5 years of
pharmaceutical experience or a MS in Statistics/Biostatistics and
at least 5-8 years of pharmaceutical experience Strong pre-clinical
and non-clinical experience is required Must have strong technical
competence. Capability to provide statistical leadership to
cross-functional teams. Sound understanding of design of
experiments, assay development, and statistical applications for
preclinical research Interest in biology, graduate level training
preferred. Good knowledge of drug development regulations pertinent
to statistical analysis Preferred candidates will have good
computational skills in SAS, R, or S-Plus.
Keywords: Unicon Pharma, Cambridge , Statistician III, Other , Cambridge, Massachusetts
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