Senior Scientist, Medicinal Chemistry
Company: Civetta Therapeutics
Posted on: October 15, 2020
Location: US-MA-CambridgeID: 2020-1343# of Openings : 1Category:
Research & DevelopmentAddress: 10 Wilson RoadOverview
Civetta Therapeutics is recently founded small molecule discovery
company located in the biotechnology hub of Cambridge (MA), backed
by Deerfield management and spun out of Dana-Farber Cancer
Institute and the Broad Institute. We are advancing the vision of
our founders, Drs. William Sellers (DFCI/Broad) and Eric Fischer
(DFCI), to develop new medicines, targeting beta-propeller proteins
to treat a range of diseases including cancer. We are building a
world-class team of researchers to deliver on this promise. If you
are a talented life sciences professional who brings energy,
passion and talent, we invite you to apply to join our exciting and
Civetta is seeking to hire a Senior Scientist in Medicinal
Chemistry to contribute to our targeted drug discovery programs and
the development of our beta-propeller platform. We are building a
drug discovery platform to enable basic research and deliver
clinical candidates on multiple promising targets. We are seeking a
medicinal chemist with significant pharmaceutical industry
experience to join our multi-disciplinary team to aid and support
all our target identification, hit optimization and clinical
candidate discovery efforts.
- Medicinal chemistry support for specific drug discovery
programs including intellectual contributions to all stages of drug
discovery from compound design & evaluation, IP protection through
to development strategies for the molecule.
- Contribute to the development of our platform by enhancing our
medicinal chemistry capabilities and resources.
- Management of chemistry CROs to enable company project and
- Collaborate with chemistry, biochemistry, and biology
colleagues to contribute and evaluate progress towards
- Prepare reports and presentations for leadership and to
participate in internal/external meetings.
- PhD in Organic or Medicinal Chemistry with 7+ years of
experience in medicinal chemistry in a biotech or pharma setting
and a demonstrated track record of contributions to identification
of development candidates. BS/MS candidates with an exceptional
track record and > 10 years of experience will also be
- A solid understanding of synthetic methodology, SAR driven
compound optimization, use of modelling software and experience in
structure-based design are required.
- Knowledge of ADME/PK assays, enzymology, pharmacology, chemical
biology and fragment-based lead discovery will be an
- Experience working with/managing synthetic chemistry CROs will
also be helpful.
- Enthusiasm for building internal and external chemistry teams
and to mentor junior colleagues desired.
- As a long-term goal, some laboratory work can be expected.
Civetta Therapeutics provides equal employment opportunities (EEO)
to all employees and applicants for employment without regard to
religion, race, creed, color, sex, sexual orientation, alienage or
citizenship status, national origin, age, marital status,
pregnancy, disability, veteran or military status, predisposing
genetic characteristics or any other characteristic protected by
applicable federal, state or local law
Keywords: Civetta Therapeutics, Cambridge , Senior Scientist, Medicinal Chemistry, Other , Cambridge, Massachusetts
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