Senior Principal Researcher - Discovery Sciences

Company: Eisai
Location: Cambridge
Posted on: October 10, 2020

Job Description:

At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai s human health care (hhc) mission. We re a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer s disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.

SENIOR PRINCIPAL RESEARCHER (DISCOVERY SCIENCES):

The candidate should demonstrate the following skills:

* Work in aseptic conditions and maintain cultures of various cell types related to CNS projects

* Experience with human primary / iPSC neuronal cell cultures

* Screening of ASO-based drug candidates in high-throughput cell-based assays

* Experience in antisense-based target validation is a plus

* Hands-on experience with various molecular/cell biology techniques are required; including nucleic acid isolation, qPCR methods, ELISA, IHC/ Western blot

* Experience with in vivo tissue handling, tissue homogenization and RNA isolation is a plus

* Ability to work in a cross functional environment

Qualifications and Experience:

* MS in biology or related field with 5 plus years of drug discovery experience in Biotech or Pharma setting.

* Experience in working with anti-sense oligonucleotide and small molecule field is required.

Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.

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Keywords: Eisai, Cambridge , Senior Principal Researcher - Discovery Sciences, Other , Cambridge, Massachusetts