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Principal Scientist

Company: Amazon Workforce Staffing
Location: Cambridge
Posted on: September 17, 2020

Job Description:

Principal Scientist, Immune Cell Therapy Pipeline Company: Colorado School of Mines Alumni

Location: Cambridge

Posted on: September 12, 2020

Job Description:

National Postdoctoral Association Career Center PrincipalScientist, Immune Cell Therapy Pipeline

CB Principal Scientist, Immune Cell Therapy Pipeline CatamaranBio, a newly-formed SV Health Investors biotechnology company, isbuilding a pipeline of effective and safe off-the-shelf celltherapy products for patients with cancer and immune disordersusing its integrated engineering and manufacturing TAILWIND TMPlatform.

Job Summary

Catamaran Bio is seeking a highly motivated, experienced, andcreative individual with expertise in cancer immunology and celltherapy to be a key driver in our preclinical research efforts toadvance our best-in-class Immune Cell Therapies for Oncology. Thisposition is an exciting opportunity to lead candidate selectionactivities, through preclinical studies to IND submission.

Job Responsibilities

Lead a project team to select drug candidates for clinicaltesting of our cell therapy products

Create a project map, candidate selection criteria, flow chart,timelines, and resourcing plan for preclinical data packageexecution

Lead the assessment and implementation of appropriate modelsystems and assays for activity and toxicity evaluation to supportIND filing

Contribute to the development of strategies for patientselection, and design and execute on a supportive experimental dataset

Work closely with cross functional project team contributors tocoordinate input from specialized areas of expertise, ensureeffective data sharing, and enable smooth project transitions

Lead and manage a scientific team in the design and developmentof a preclinical data package, including engineering of primaryimmune cells and in vitro/ex vivo assessment of cell functions

Manage and mentor scientists in the design of experiments,rigorous execution of bench work, troubleshooting of assays,analysis of data, and communication of findings

Become the subject matter expert for the preclinical project

Make intellectual and technical contributions broadly acrossCatamaran projects and strategic initiatives

Work collaboratively with internal and external industry andacademic teams

Manage projects with vendors and CROs

Write, edit, and review reports, records, and documents for IPand regulatory filings

Present results at internal and external meetings

Contribute to building a positive, team-oriented biotechculture

Requirements

Education, Experience and Qualifications

PhD in immunology, immuno-oncology, cancer biology or relatedfield with 5+ years of industry experience

Demonstrated experience working in cross-functional teams

Project team leadership experience

Previous experience with IND submission a plus

Technical expertise with in vitro/ex vivo immunologystudies, including functional immune cell assessments using primarycell isolation, multi-color flow cytometry, cytotoxicity assays,and cytokine quantitation

Subject matter expertise in NK cell biology and tumorimmunology, and experience with human immune cell engineering ispreferred

Ability to quickly learn and adapt in a fast paced, rapidlydeveloping environment

Creativity and intellectual rigor with experience in drivingresearch projects, including the design, execution, and analysis ofexperiments

High level of motivation and ability to work both independentlyand in collaborative teams

Flawless record keeping and multi-tasking abilities

Excellent organization and communication skills

Catamaran Bio is proud to be an equal opportunity workplace andis an affirmative action employer. We are committed to equalemployment opportunity regardless of race, color, ancestry,religion, sex, national origin, sexual orientation, age,citizenship, marital status, disability, gender identity or Veteranstatus .

Job Information

Job ID: 54365062

Location:

Cambridge, Massachusetts, United States

Position Title: Principal Scientist, Immune Cell TherapyPipeline

Senior Principal Scientist Director (TBD),... N

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Keywords: Colorado School of Mines Alumni, Cambridge , Principal Scientist, Immune Cell Therapy Pipeline, Other , Cambridge, Massachusetts

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Keywords: Amazon Workforce Staffing, Cambridge , Principal Scientist, Other , Cambridge, Massachusetts

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