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Director, Supply Chain

Company: Amazon Workforce Staffing
Location: Cambridge
Posted on: September 17, 2020

Job Description:

Company: Spero Therapeutics

Location: Cambridge

Posted on: September 12, 2020

Job Description:

Spero Therapeutics (Nasdaq: SPRO) is a multi-asset clinicalstage biopharmaceutical company in Cambridge, Mass. We are highlycommitted to advancing novel treatment approaches for bacterialinfections with a world-class team of biotechnological andbiopharmaceutical experts. The company has a pipeline of novel andhighly differentiated antibacterial and rare disease productcandidates focused on the unmet needs of patients with multi-drugresistant (MDR) bacterial infections. Spero’s lead productcandidate, Tebipenem HBr, is an oral carbapenem currently beingevaluated in a pivotal Phase 3 clinical trial for the treatment ofcomplicated urinary tract infections. Spero is also advancingSPR720, its oral antimicrobial agent in development for thetreatment of nontuberculous mycobacterial (NTM) pulmonary disease,a rare orphan disease. Spero’s third product candidate, SPR206, isan IV-administered agent being developed as an innovative option totreat MDR Gram-negative bacterial infections.

We sincerely believe that our novel product candidates will havemeaningful impact on patient health and significant commercialapplications for the treatment of MDR infections in both thehospital and community settings.

General Scope and Summary of Role

Spero Therapeutics is searching for an experienced leader for ahighly visible role as Director, Supply Chain. The successfulcandidate will be part of a team responsible for overseeing thesupply chain for products across Spero’s portfolio, and for leadingglobal clinical and commercial logistics operations. The successfulcandidate will be responsible for planning, production and materialmanagement, labeling and packaging operations, logistics, anddistribution of clinical and commercial supply.

What You’ll Do

Lead all aspects of API, drug product, and finished goods supplyplanning, capacity planning, labeling/packaging development andoperations, production scheduling and execution, logistics, andrisk management for Spero’s products

Lead all aspects of supplying Third Party Logistics (3PL)provider to enable distribution. Ensure inventory goals are met andwork closely with Finance, Commercial, and IT teams to ensureaccurate reporting

Lead and actively manages relationships with finished goodsContract Manufacturing Organizations to ensure production andinventory targets are communicated and met

Lead global clinical and commercial logistics operationsincluding the build and implementation of processes to managedomestic and international shipments

Lead and facilitates the Sales and Operations Planning processacross commercial programs

Collaborate with CMC team to ensure drug substance and drugproduct availability and Commercial Operations team to provideforecast data for inventory maintenance

Work closely with Commercial Operations and Regulatory Affairsto actively manage label and secondary package design operationsincluding development, proof review/approval, and communication toexternal partners

Provide input and data for Regulatory filings

Actively communicates, collaborates with, and contributes toother functional areas including Commercial Operations, RegulatoryAffairs, Quality Assurance, CMC, Finance, and external partners anddrives to achieve the best business results for the company

Provide support to CMC in commercial and R&D programs

Participate in the Supply Chain team and supports ClinicalSupply Chain activities, as required

What You’ll Need

Bachelor’s degree in a technical or scientific discipline

10+ years of relevant supply chain experience in thepharmaceutical industry

Ability to travel up to 25%; must be able to travelinternationally. Prior International experience is a plus.

Broad experience and proven track record in pharmaceuticalsupply chain management including planning, CMO oversight, labelingand packaging, and logistics/distribution.

Experience in cGMP operations; leading and contributing tocross-functional teams

Experience with sterile products, oral dosage forms, and productadministration preferred

Experience in Commercial and Clinical Manufacturing Operationsand/or Quality are a plus

Excellent communication and collaboration skills across levels,functions, and organizations in a fast paced environment as well asa proven ability to execute and contribute strategically to achieveresults in a virtual setting are a must.

Excitement about the vision and mission of Spero

By joining our committed and highly motivated team, you’llexperience a workplace culture that is inclusive, fair,challenging, supportive, and respectful. Spero’s culture is onethat emphasizes “servant leadership,” or putting ego aside andworking for the benefit of the team and our patients and values ourcolleagues’ opinions and celebrates accomplishments in service ofpatients.

What's your citizenship / employment eligibility? *

Keywords: Spero Therapeutics, Cambridge , Director, Supply Chain, Other , Cambridge, Massachusetts

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Keywords: Amazon Workforce Staffing, Cambridge , Director, Supply Chain, Other , Cambridge, Massachusetts

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