CambridgeRecruiter Since 2001
the smart solution for Cambridge jobs

Senior Scientist, Translational

Company: Recruitomics Consulting
Location: Cambridge
Posted on: September 17, 2020

Job Description:

About Revitope

Revitope Oncology ( is an early stage biotechnology company located in the heart of Cambridge, Massachusetts, with the vision to drive the development of next-generation immunotherapies to treat solid and liquid tumors. Immunotherapies are redefining how cancer is treated and are beginning to show unprecedented deep and durable responses in multiple tumor types. In particular, redirecting T cells to tumors is a successful strategy for immunotherapy but to date severe toxicities arising from targeting of healthy tissues is limiting their full potential.

Revitope is developing a new class of T-cell engaging immunotherapies designed to focus immunological activation specifically to the cancer cell surface while avoiding unwanted toxicity in healthy tissues. Our approach also expands antigenic targeting space through exploiting two antigens co-expressed on tumor cells. Revitope’s proprietary technology platform and enabling skill base lends itself to partnering opportunities as well as to driving internal programs towards the clinic. Revitope has already signed a significant collaboration and is actively engaged in discussions with others.

We are now looking to add a highly motivated and enthusiastic Senior Scientist to join our growing cross-functional team. This individual will develop new in vitro assays to characterize Revitope platform as well as therapeutics advancing in the pipeline. This is a unique opportunity to develop novel preclinical assays and adapt/evolve key assays to formats suitable for clinical analysis, while contributing to the development of new biologics drugs for cancer immunotherapy in a highly collegial start-up biotech.

Key Responsibilities Act as company expert in the areas of novel assay development and transition of assays to formats suitable for clinical assessment; provide valuable insight into the global understanding of the Revitope platform pre-clinically as well as providing critical assays for decision making clinically.

Guide design of novel assays needed for platform development and therapeutic evaluation.

In concert with Biology team devise strategies for evaluating the expression of candidate targets, assessing toxicity risk, and informing final target selection

Lead small group of in-house research associates while maintaining a strong hands-on presence in the laboratory.

Train and/or oversee research associates to develop novel assays including assay design and conduct, data collection, review and interpretation.

Work collaboratively and seamlessly with in vitro, in vivo and protein sciences colleagues as well as external experts to effectively investigate new candidate molecules.

Effectively document experimental analyses and communicate within the organization and externally.

Participate in strategic and priority setting discussions with senior leadership and project teams and design appropriate assays and plans in line with company goals and timelines.

Review and ensure the quality of scientific data to meet regulatory expectations.

Author peer-reviewed publications, technical and regulatory documents to support advancement of therapeutics to clinical testing.

Required Qualifications PhD or equivalent in biological sciences, immunology, oncology, pharmacology or a related discipline with a minimum of 5-8 years in vitro experience in biotech/pharma; background in the area of T cell redirection and/or CART therapeutics preferred.

Leader with strong track record in the development of novel assays including experimental design, standardization, data analysis and interpretation, statistics and transformation of preclinical assays to formats suitable for clinical analyses.

Highly technically proficient in broad array of in vitro assay approaches and techniques for investigating effects of antibody-based therapeutics on cells.

Experience in diverse approaches to studying protein expression (flow cytometry, immunofluorescence, immunohistochemistry, proteomics) highly preferred.

Experience in protease biology a plus.

Demonstrated ability to interpret data from single experiments and integrate data from diverse experiments to draw clear conclusions.

Highly motivated strong team player with experience leading in-house projects as well as studies conducted at academic collaborators.

Experience leading and managing direct or matrixed reports and demonstrated ability to develop young scientists.

Ability to manage timelines and set priorities consistent with goals for advancing therapeutics.

Possession of strong communication skills, both written and verbal, to clearly convey complex strategies and scientific data and tailor messaging to diverse audiences

Ability to work collaboratively, inclusively, ethically and thrive in the fast paced and changing environment of a small biotech.

What We Offer

This is a unique opportunity to be among the first employees at a fast-paced, rapidly growing biotech startup with a bold vision. As an early employee, you will have a direct influence on the science, opportunities to gain new skills and be joining an ambitious, innovative, and collaborative team.

Revitope is deeply committed to diversity, equality, and inclusion in all of its practices, especially when it comes to growing our team. We hope to continue to build a company whose culture promotes inclusion and embraces how rewarding it is to work with individuals from all walks of life.

Keywords: Recruitomics Consulting, Cambridge , Senior Scientist, Translational, Other , Cambridge, Massachusetts

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category

Other Other Jobs

Part-Time Amazon Package Sorter with Sign-on Bonus!
Description: Full-time Warehouse Team Member - 500 sign-on bonus Hourly pay rate: Earn 15.75 - 16.75/hr, plus benefits and a 500 sign-on bonus.Limited Time OpportunityLocation: Taunton, MAJob opportunities vary (more...)
Company: Amazon Workforce Staffing
Location: East Providence
Posted on: 09/20/2020

Part-Time Teller, Hyde Park, Boston, MA
Description: Part-Time Teller, Hyde Park, Boston, MA-----2002144--Description--The Representative, Teller processes face-to-face Customer transactions for a variety of routine financial transactions. -- Responsibilities (more...)
Company: Santander Holdings USA Inc
Location: Weymouth
Posted on: 09/20/2020

Amazon Workforce Staffing: Seasonal Part-Time Warehouse Team Member - $500 Sign-On Bonus
Description: Seasonal Part-time Warehouse Team Member 500 sign-on bonusHourly pay rate:Earn 15.25- 18.25/hr, plus benefits and a 500 bonus The base pay for this role is 15.25/hr. We are offering temporary shift (more...)
Company: Amazon Workforce Staffing
Location: Taunton
Posted on: 09/20/2020

CDL-A Refrigerated Truck Driver - Flexible Home Time!
Description: CDL-A TRUCK DRIVER JOBS -REFRIGERATED FREIGHT Top Pay Flexible Home Time NEW Address-to-Address Mileage Pay More Accurately Reflects The Miles YOU Drive Join a growing fleet As a Roehl refrigerated (more...)
Company: Roehl Transport Inc
Location: Taunton
Posted on: 09/20/2020

Customer Service/Sales
Description: Customer Service/Sales 305583291 Concord, New Hampshire, US, 03301 Position Purpose: Customer Service/Sales associates provide fast, friendly service by actively seeking out customers to assess their (more...)
Company: The Home Depot
Location: Concord
Posted on: 09/20/2020

Booth rental - Unique opportunity
Description: Anjou Hair Studio, voted Concord, NH best salon five years running has a rare booth rental
Company: Anjou Hair Studio
Location: Concord
Posted on: 09/20/2020

Veterans Preferred - Paid Apprenticeships and Paid Online Cyber Degrees
Description: Military Veterans are Encouraged to Apply. Earn your degree while you work. Employers are hiring nationwide You don't have to choose between going back
Company: Purdue University
Location: Concord
Posted on: 09/20/2020

Seasonal Part-Time Amazon Package Sorter With $500 Sign-on Bonus
Description: Full-time Warehouse Team Member - 500 sign-on bonus Hourly pay rate: Earn 15.75 - 16.75/hr, plus benefits and a 500 sign-on bonus.Limited Time OpportunityLocation: Taunton, MAJob opportunities vary (more...)
Company: Amazon Workforce Staffing
Location: East Providence
Posted on: 09/20/2020

Amazon Online Order Shopper (Part-Time Regular) - Earn $15/hr or more
Description: Schedule:--Part-Time Regular br br Salary br Earn 15.00/hr or more br br Amazon remains open as an essential service to serve our communities delivering critical supplies directly to the doorsteps (more...)
Company: Amazon
Location: Weymouth
Posted on: 09/20/2020

Nursing Aides (CNA & HHA) Multiple Shifts
Description: We are currently hiring Home Health Aides HHAs and Certified Nursing Assistants CNAs for various open positions including but not limited to: AM, PM AND NIGHT SHIFTS WEEKDAYS OR WEEKENDS OR BOTH (more...)
Company: CareInHomes
Location: East Providence
Posted on: 09/20/2020

Log In or Create An Account

Get the latest Massachusetts jobs by following @recnetMA on Twitter!

Cambridge RSS job feeds