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Associate Director, ADC

Company: Amazon Workforce Staffing
Location: Cambridge
Posted on: September 17, 2020

Job Description:

Company: NATIONAL POSTDOCTORAL ASSN

Location: Cambridge

Posted on: September 12, 2020

Job Description:

National Postdoctoral Association Career Center In this role,you’ll have an opportunity to support the advancement of Mersana’sAntibodies and ADCs within our Analytical R&D organization.Since we are on the cutting edge of a new therapeutic category withits own unique testing requirements, we will take your existingexpertise in analytical development, method development,validation/qualification and transfer, and complement it with ourknowledge of polymer and small molecule chemistry. You’ll also havean opportunity to form close partnerships with CMOs, CROs andinternal stakeholders. If you are passionate about our science anda curious scientist who enjoys being creative and not afraid to bechallenged, this is a great opportunity to have an impact onMersana’s novel platform. We will work as a team to expand ourknowledge base of our ADCs in order to enable their evolutiontowards optimized cancer therapies. You will be immersed in alearning organization, with a need to bring an open mind and aninterest in mastering this new therapeutic space at a rapid pace.You will have the potential to hire and mentor staff as the companygrows.

How do you know if you’re the right fit?

The successful candidate will:

Drive method development, qualification and validation forMersana’s ADCs and key intermediates such as linker-payloads,antibodies and other biologics

Have broad understanding of CMC, including phase-appropriatedevelopment amongst the different functions

Be experienced in managing CRO’s to deliver on Analytical goalsunder tight and often shifting timelines

Requirements

This is typically a role best suited for Ph.D. degreedcandidates in analytical chemistry, chemistry, biochemistry, or arelated discipline with a minimum of 10 years of experience, atleast 7 of which is in the biotech or pharmaceutical industry or ata CRO. M.S. degree candidates with 10+ years of experience will beconsidered.

Additionally, you’ll have:

Experience with methods and typical specifications for smallmolecule, polymer, protein, antibody and ADC analysis

Knowledge of analytical requirements for intermediates, drugsubstance and drug product

Direct experience with technology transfer within a company,to/from CMOs, and between international facilities

Knowledge of ICH and FDA guidelines, and experience authoringand reviewing regulatory submissions

Experience with biological assays such as binding ELISA andcell-based potency is desirable

Knowledge of process development early/clinical/commercial orformulation development for recombinant protein therapeutics,antibodies, antibody fragments, antibody drug conjugates (ADC) isdesired

Outstanding communication and organizational skills required.Works effectively and collaboratively in teams, is energetic,highly self-motivated and able to work efficiently, independentlyand productively in a growing company environment.

A solid track record of publications, presentations, andachievements.

Position is eligible for bonus, option awards and benefitsincluding medical, dental and life insurance, 401(k) participation,vacation and paid holidays.

Successful candidate must be authorized to work in the UnitedStates.

Mersana Therapeutics, Inc. is an equal opportunity employer.

Job Information

Job ID: 54280446

Location:

Cambridge, Massachusetts, United States

Position Title: Associate Director, ADC - mAb Analytics

Company Name: Mersana Therapeutics

Job Function: Biotherapeutics

Job Type: Full-Time

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