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Senior Scientist, Biophysics

Company: Civetta Therapeutics
Location: Cambridge
Posted on: September 15, 2020

Job Description:

Location: US-MA-CambridgeID: 2# of Openings : 1Category: Research & DevelopmentAddress: 650 East Kendall Street

Overview

Deerfield Management is an investment management firm committed to improving healthcare through investment, information and philanthropy. We have just launched a new company called Civetta Therapeutics located in Cambridge, MA that was founded by William Sellers (Broad Institute and Dana-Farber Cancer Institute) and Eric Fischer (Dana Farber Cancer Institute and Harvard Medical School). We are looking to engage a high-quality team of researchers to advance new medicines through small molecule intervention targeting propeller domains with the goal of developing important therapeutics for cancer and other indications. If you are a talented life sciences professional that can bring significant energy, passion and talent to the team, we welcome the opportunity to consider you for a position in this exciting, new company.

About the Founders:

William Sellers is a core institute member of the Broad Institute of MIT and Harvard, a faculty member at Harvard Medical School, and faculty member and senior advisor to the president for experimental therapeutics at the Dana-Farber Cancer Institute.

Eric Fischer is an Assistant Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and an Independent Investigator, Dana-Farber Cancer Institute.

Responsibilities

Key Responsibilities:

  • Design and develop robust SPR assays for essential incorporation to our drug discovery screening cascades
  • Routinely and consistently evaluate small molecules for interaction in multiple biophysical assays

    Qualifications

    Required Skills and Qualifications:
    • PhD preferred, with degree of study in biophysics, biochemistry, biology, chemical biology or equivalent
    • 5+ years of pharmaceutical/biotech industry experience in SPR assay development methods in assessing protein-small molecule and protein-protein interactions with consistent, high-quality data analysis and independent troubleshooting
    • Additional experience with other biophysical methods (BLI, MST, ITC) is preferred
    • Familiarity with enzymatic and PPI biochemical assay development a plus
    • Ability to balance multiple projects at different hit triage stages
    • Exceptional communication skills, and ability to effectively present data within the company and to other stakeholders
    • Adept at leading and working within cross-functional scientific teams, and able to work effectively with teams to deliver project data within timelines
    • Strong publication record of biophysical data and analysis in peer-reviewed journals
      Civetta Therapeutics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

      PM18

      #LI-DNI

Keywords: Civetta Therapeutics, Cambridge , Senior Scientist, Biophysics, Other , Cambridge, Massachusetts

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