Senior/Executive Director, Biologics Development

Company: HCPro, Inc.
Location: Cambridge
Posted on: September 14, 2020

Job Description:

Mersana Therapeutics, Inc. (Nasdaq: MRSN) is a clinical-stage biopharmaceutical company using its differentiated and proprietary ADC platforms to develop highly targeted drugs with increased tolerability and expanded opportunities to deliver meaningful clinical benefit to cancer patients. Mersana's lead product candidate, XMT-1536, is in a Phase 1 clinical trial in patients with tumors expressing NaPi2b, including ovarian cancer and NSCLC adenocarcinoma. In addition, multiple partners are using Mersana's platform to advance their ADC pipelines.

Mersana's mission is to discover and develop life-changing antibody-drug conjugates for patients fighting cancer. We seek individuals who share our excitement about the possibilities our proprietary drug conjugation platforms offer, as well as our commitment to making a meaningful difference for patients and their families. At Mersana we have a highly collaborative culture and believe that our collective ability to make a difference exceeds the sum of our individual efforts. MT

Senior/Executive Director, Biologics Development

Mersana Therapeutics

Cambridge, Massachusetts, United States

9 hours ago

Description

Mersana Therapeutics, Inc. (Nasdaq: MRSN) is a clinical-stage biopharmaceutical company using its differentiated and proprietary ADC platforms to develop highly targeted drugs with increased tolerability and expanded opportunities to deliver meaningful clinical benefit to cancer patients. Mersana's lead product candidate, XMT-1536, is in a Phase 1 clinical trial in patients with tumors expressing NaPi2b, including ovarian cancer and NSCLC adenocarcinoma. In addition, multiple partners are using Mersana's platform to advance their ADC pipelines.

Mersana's mission is to discover and develop life-changing antibody-drug conjugates for patients fighting cancer. We seek individuals who share our excitement about the possibilities our proprietary drug conjugation platforms offer, as well as our commitment to making a meaningful difference for patients and their families. At Mersana we have a highly collaborative culture and believe that our collective ability to make a difference exceeds the sum of our individual efforts.

What's in it for you?

In this role, you will have the opportunity to lead all process development, scale-up, and external manufacturing efforts for Mersana mAbs, including cell line development, bioreactor production, and downstream purification. You will form close partnerships with internal and external stakeholders including CMOs. To be successful you will bring your organizational and people leadership strengths as well as your demonstrated technical expertise in biologics development. If you are not yet an expert in some of the following: cell line development, bioreactor production, biologics purification, scale-up and unit operation research, tech transfer activities, or biologics process characterization and validation, you'll have an opportunity to dive deeper and learn. This position reports to the SVP, CMC.

How do you know you're the right fit?

You'll have demonstrated successes, and your experience will lend well to the following key responsibilities:

* Ensuring continuity of mAb supply for current programs XMT-1536 and XMT-1592) as well as mAb supply for future clinical development programs.

* Leading CMO selection, oversight, and management for mAb production.

* Participating in technology transfer projects as well as troubleshooting activities related to external manufacturing.

* Participating in Process Characterization activities for our lead molecule XMT-1536, and prepare for the initiation of PPQs

* Representing Mersana externally with vendors and partners, as the technical expert on biopharmaceutical production.

* Working closely with counterparts in Drug Substance and Drug Product Development to ensure a seamless manufacturing strategy and execution.

* Leading of team of 2 engaged in antibody development and production

Requirements

This is typically a role best suited for candidates possessing a Graduate Degree in Life Sciences, Physical Sciences, Engineering, Biopharmaceutical Production, Pharmaceutical Sciences or related scientific discipline required; PhD preferred with 10 years' experience in the biotechnology or pharmaceutical industry. Additionally, you'll possess:

* Technical expertise in one or more of the following areas: cell line development, bioreactor production, biologics purification (preferred), scale-up and unit operation research, tech transfer activities, biologics process characterization and validation.

* Demonstrated people and organizational leadership success. The role requires a leader willing to be both a "coach and a player"

* Ability to negotiate and dramatically influence to have a positive impact inside and outside the organization.

* Excellent interpersonal, oral and written communication skills.

* Position may require up to 30% travel

Job Information

* Job ID: 54649853

* Location:

Cambridge, Massachusetts, United States

* Position Title: Senior/Executive Director, Biologics Development

* Company Name: Mersana Therapeutics

* Job Function: Biotherapeutics

* Job Type: Full-Time This is typically a role best suited for candidates possessing a Graduate Degree in Life Sciences, Physical Sciences, Engineering, Biopharmaceutical Production, Pharmaceutical Sciences or related scientific discipline required; PhD preferred with 10 years' experience in the biotechnology or pharmaceutical industry. Additionally, you'll possess:

* Technical expertise in one or more of the following areas: cell line development, bioreactor production, biologics purification (preferred), scale-up and unit operation research, tech transfer activities, biologics process characterization and validation.

* Demonstrated people and organizational leadership success. The role requires a leader willing to be both a "coach and a player"

* Ability to negotiate and dramatically influence to have a positive impact inside and outside the organization.

* Excellent interpersonal, oral and written communication skills.

* Position may require up to 30% travel

Keywords: HCPro, Inc., Cambridge , Senior/Executive Director, Biologics Development, Other , Cambridge, Massachusetts