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Scientist, Research Analytical Discovery

Company: Ultragenyx Pharmaceutical
Location: Cambridge
Posted on: September 14, 2020

Job Description:

Ultragenyx is a commercial-stage biopharmaceutical company committed to developing and commercializing novel therapies for the treatment of rare and ultra-rare genetic diseases. The company has rapidly built a diverse portfolio of small molecules, biologics, gene therapies and nucleic acids to target debilitating genetic diseases for which the unmet medical need is high, the biology for treatment is clear, and for which there are typically no approved therapies treating the underlying disease. Ultragenyx Gene Therapy is headquartered in Cambridge, MA with additional locations in Woburn, MA. We are looking for exceptional individuals who share our passion for developing novel therapies to treat rare diseases and advancing the field of gene therapy. Developing new treatments for rare genetic diseases is challenging work. It takes courage, talent, and dedication to look past the easy answers and uncover new solutions that can make a meaningful impact. At Ultragenyx we push each other to perform at our very best, because we never lose sight of our mission – to make a difference in our patients’ lives. Come join our team during this exciting time of growth and opportunities! During the COVID-19 Outbreak we are committed to our hiring process. The health and safety of our employees and prospective employees take priority which means at this time our process will include remote based web-ex video discussions, interviews & onboarding. Position Summary ultrainnovative – Tackle rare and dynamic challenges The candidate will lead advancement of innovative AAV-based therapeutics through development and execution of a variety of research methods including molecular, biochemical, biophysical and cell-based assays. Responsibilities including, but not limited to Develop and qualify analytical research methods to measure and monitor key quality attributes for AAV therapeutic materials Execute cell-based, biophysical, biochemical and molecular analytical research methods to support process development of AAV pipeline candidates Execute cell-based, biophysical, biochemical and molecular analytical research methods to support AAV manufacturing platform development Work with senior research staff to develop and troubleshoot methods Work with senior research staff to evaluate and implement new analytical instrumentation and new technologies Communicate results and research progress during team and departmental meetings Prepare, write, analyze, and present technical data and reports Work as part of a cross-functional team to drive innovation in a scientifically stimulating, patient-focused research environment. Requirements PhD in Cell Biology, Molecular Biology, Microbiology, Biochemistry, Virology or related discipline with applicable academic or industrial experience in method development, or MS with 6+ year of industrial experience in method development, or BS with 9+ years of industrial experience in method development Experience with mammalian cell culture and quantitative PCR methods required. Experience in molecular biology, protein biochemistry, biophysical characterization, and immunoassays is required. Experience with CE-SDS, Western blot, Southern blot, flow cytometry and NGS methodology preferred. Experience with viral vectors is preferred. Experience with cell-based assays is preferred. Should be highly motivated, have excellent organizational and communication skills, and be able to multitask in a fast-paced environment with changing priorities Ability to execute and follow projects through to completion with high-quality, timely documentation Ability to lead, mentor and execute effectively in a collaborative team environment where results are achieved through influence and the incorporation of multiple points of view #LI-TR1 Ultragenyx Pharmaceutical is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status. Reasonable accommodation will be provided for qualified individuals with disabilities and for qualified disabled veterans in job application procedures, as required by applicable law. If you have any difficulty using our online application system and need an accommodation due to a disability, you may contact Talent Acquisition by calling: (415) 483-8800 or by emailing us at talentacquisition@ultragenyx.com. For electronic email and mail inquiries, please include a description of your requested accommodation, your name and contact information. Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

Keywords: Ultragenyx Pharmaceutical, Cambridge , Scientist, Research Analytical Discovery, Other , Cambridge, Massachusetts

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