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Senior Research Associate, Oncology Drug Discovery

Company: Versant NewCo
Location: Cambridge
Posted on: June 20, 2022

Job Description:

Senior Research Associate, Oncology Drug DiscoveryLocation: Cambridge, MA This position will serve a critical role in establishing and running cell-based assays to inform target biology and help drive our small molecule drug discovery programs. This position is ideal for a talented highly motivated result driven individual who will thrive in a fast-paced environment. A unique opportunity for a motivated and experienced team player to join an early-stage company to support drug discovery programs, interface with team members on the development of unique chemical matter to solve novel biological problems. This person will work in multidisciplinary teams to develop, validate and optimize novel molecular matter, will help design and develop first of kind novel in silico drug design platform to develop a new class of novel small molecules.Responsibilities: --- Designing and executing experiments to inform target biology using a of variety approaches, including cell line engineering, analyzing signaling pathways and characterization of cell death mechanism(s) --- Develop and execute HTS assays --- Designing and conducting mechanism of action studies --- Developing in vitro and in- vivo pharmacodynamic readouts --- Genetic manipulation of cells utilizing knockdown or knockout and overexpression of protein for target validation --- Using decision making, organizational and communications skills to effectively collaborate with biologist and other scientist from a variety of backgrounds --- Documentation and presentation of data, findings and experimental conclusions at various meetings including project team, department, and company meetingsQualifications: --- BS/MS in biochemistry, molecular biology, cell biology or a related field with 1-3 years of industry experience in biological assays/ in vitro pharmacology (with oncology experience preferred but not required) --- Deep understanding of cell culture, assay implementation and data processing with excellent scientific rigor --- Experience in diverse molecular and cell biology techniques including siRNA, CRISPR, and immunoassays --- Proficiency in using software such as, GraphPad, Microsoft office etc. --- Strong ability to pay attention to detail as well as the ability to balance multiple objectives at the same time --- Pro-active problem solver --- Flexibility to navigate a dynamic early-stage biotech environment --- Strong cross functional communication, collaboration skills with focus on respect and trust --- Willingness to ask questions, be open to new ideas and manage ambiguityInterested candidates should submit a CV and cover letter to Careers@nestedtx.comNested Therapeutics is a Cambridge-based VC-backed stealth biotech focused on discovering and developing next generation precision oncology small molecule medicines. We are advancing drug discovery programs based on a platform that combines insights in cancer biology, structural biology, biophysics and chemical biology to identify and characterize novel druggable domains of protein targets.

Keywords: Versant NewCo, Cambridge , Senior Research Associate, Oncology Drug Discovery, Healthcare , Cambridge, Massachusetts

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