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Principal Scientist, Immuno-Oncology, Lab Head

Company: Sanofi
Location: Cambridge
Posted on: June 19, 2022

Job Description:

Position Overview:Sanofi Immuno-Oncology Therapeutic Area is seeking an outstanding scientist with background in immunology, especially in regulatory T (Treg) cell biology and experience in drug development as a Principal Scientist. This individual will be spearheading efforts to develop multi-specific biologics to target Treg cells in the tumor microenvironment. This position is based in Cambridge, Massachusetts, USA. The successful candidate will support ongoing early research programs as well as developing new projects, contributing to the growth of the Sanofi pipeline.Key Responsibilities:

  • Responsible for applying scientific expertise to initiate and develop new projects.
  • Work collaboratively with other functional areas, including Precision Oncology, In Vivo Pharmacology and Translational Sciences for target discovery and validation.
  • Lead cross-functional research teams, ensuring timely progression of the projects from early concepts to FIH.
  • Keep abreast of the latest in basic immunological research, immune-oncology clinical development and competitive landscape.
  • Manage direct reports in a professional manner, provide effective mentorship and lead by example.Basic Qualifications:
    • Ph.D. in Immunology, Immuno-Oncology or related discipline plus a minimum of 5 years of relevant post-graduate research experience in an academic or biopharmaceutical setting.
    • Expert knowledge of tumor immunology.
    • Solid track record of independent research accomplishments in Immuno-Oncology or related discipline, as evidenced by publications in peer-reviewed journals.
    • Research experience in human Treg cells is strongly preferred.
    • Prior experience in Immuno-Oncology antibody-based drug development is strongly preferred.
    • Hands-on experience in cell isolation and phenotyping of murine and human immune populations (e.g. cell sorting, flow cytometry) and functional assessment of immune subsets in standard immunological assays and techniques (e.g. CTL assay, cell proliferation, apoptosis, cytokine/chemokine measurement).
    • Possess knowledge of various murine tumor models and technical expertise in tumor analysis.
    • A familiarity with next generation sequencing approaches for immune phenotyping and ability to collaborate with genomics/bioinformatics group in study design and data interpretation.
    • The ability to effectively communicate and lead others.
    • Must be highly collaborative and able to work independently.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.#GD-SA
      #LI-SAAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

Keywords: Sanofi, Cambridge , Principal Scientist, Immuno-Oncology, Lab Head, Healthcare , Cambridge, Massachusetts

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