Investigator, Immuno-Oncology; Cambridge, MA

Company: GlaxoSmithKline
Location: Cambridge
Posted on: May 12, 2022

Job Description:

Site Name: USA - Massachusetts - CambridgePosted Date: Feb 24 2022Are you a -scientist with -experience and -passion for drug discovery and development in the field of Immuno-Oncology? -If so, -this -Investigator role -would be an excellent opportunity to consider.The Immuno-Oncology & Combinations Research Unit (IOC RU) within the GSK Oncology organization is seeking an innovative and highly motivated -laboratory-based -Investigator to support preclinical development of immune-based therapies and validate novel cancer immunotherapies.Building on your background in immuno-oncology/immunology, you will expand state-of-the-art -in vitro -and -ex vivo -assay capabilities at a growing GSK site -and support novel target identification efforts using by characterize -immune cell function on a single cell level. -Applying a translational mindset, you will cultivate and work in a dynamic and collaborative environment -to -interrogate mechanisms of action and pharmacology of novel therapeutics, supporting GSK's diverse immuno-oncology pipeline from early discovery to -first time-in-human commitment. -We are looking for a proactive team member, who can think out of the box to solve scientific problems, who is open to the ideas of others, and has -a deep curiosity and enthusiasm for uncovering novel biology with a translational mind-set. -The investigator will be accountable for generating high quality, robust data and must have an ability to work effectively both independently and as part of a multidisciplinary matrix team. -Additionally, you will need to be a collegial team player, open to the ideas of others, and embody a truth-seeking and inclusive culture.Why You?Basic Qualifications: - - Ph.D. -in -immuno-oncology, biology or related field - -Experience with transcriptomic or proteomic single cell -preparation and -bioinformatic -analysis (10x genomics, Isoplexis) - -Hands-on experience with -co-culture systems of primary human cells to interrogate immune cell function using flow cytometry, multiplexed cytokine quantification, and transcriptomic readouts.Preferred Qualifications: - - Experience with a -wide -range of immune cells types, incl. lymphocytes, B cells -and multiple myeloid cell types, is preferred.Experience with -independently -designing, conducting, and analyzing -experiment data to functionally characterize biologics, small molecules and/or drug combinations. -Excellent communication and organizational skills, present results at project team meetings and mentor junior scientists. -Computation biology experience is ideal - -Prior experience with isolation, phenotypical and functional characterization of human tumor-infiltrating leukocytes is advantageous. -Strong communication skills -and ability to contribute in a cross-functional and global environment. -Ability to prioritize, manage time efficiently, and implement creative solutions to meet program needs. -High degree of independence, proactivity, and a strong sense of accountability. -Excellent problem-solving skills including critical and analytical thinking. -Hands-on experience to prioritize multiple projects and meet timelines while maintaining attention to detail and setting high performance standards. -Ability to understand, interpret, and communicate complex scientific data. -Why GSK? -As GSK Focuses -on -Our Values and Expectations and a Culture of Innovation, Performance, and Trust.The Successful Candidate Will Demonstrate The Following Capabilities: -Our values and expectations are at the heart of everything we do and form an important part of our culture.These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: - -Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigor and risk. -Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. -Continuously looking for opportunities to learn, build skills and share learning. -Sustaining energy and well-being. -Building strong relationships and collaboration, honest and open conversations. -Budgeting and cost-consciousness.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity -Employer, -and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value -is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting -For -the Record site.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. -GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting site.

Keywords: GlaxoSmithKline, Cambridge , Investigator, Immuno-Oncology; Cambridge, MA, Healthcare , Cambridge, Massachusetts