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Co-op: Gene Therapy

Company: Biogen
Location: Cambridge
Posted on: May 12, 2022

Job Description:

Company Description

At Biogen, our mission is clear - we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population.

We at Biogen are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients who we serve. We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included.

As an intern or co-op at Biogen, you can expect to be placed on a real project, under the guidance of experience professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.

Job Description

This application is for a 6-month student role from July - December 2022. Resume review begins in January 2022.

Work within one of several departments in Biogen's Product and Technology Development (PTD) organization engaged in laboratory activities supporting the development and characterization of therapeutic products, manufacturing processes---or new technologies.

Position Description

Product and Technical Development is looking for two co-ops to fill two separate gene therapy projects. The projects are as follows:

Biologics-Cell Line Technology
We are seeking a motivated and creative individual to join this collaborative effort between both gene therapy and biologics-cell line technologies groups to contribute to ongoing efforts to develop and engineer viral vector and biologics production mammalian host cell systems. The successful candidate will be a part of both cell line technologies teams and gain experience in cell line development in multiple therapeutic production host cell systems. The candidate will also have opportunities to be exposed to other line functions such as upstream and downstream processing through collaborations and cross-training.
Day-to-day responsibilities include passaging cultures, transfection experiments, cell line engineering, traditional molecular biology experiments, high throughput automation experiments. Data recording, interpretation, and presentation for ongoing work in group meetings are expected.
Engineered cell lines will be the backbone of multiple efforts to increase AAV/mAb productivity and further understand how to drive product quality. By the end of the coop, the candidate will have hands-on experience in multiple industry-leading biologics production technologies and contribute to critical raw materials (cell lines) for the production of therapies.

Gene Therapy Drug Product
We are seeking a motivated individual to join the Gene Therapy Drug Product team and help to develop new viral vector fill and finish technologies. This opportunity grants you a chance to learn about the drug product manufacturing development process including formulation and process development.
You will work with Biogen engineer(s) to develop formulations and processes to enable a stable lyophilized drug product. The candidate will perform a variety of functions to support this goal consisting of formulation screening studies, forced degradation studies, and accelerated stability screening. Candidates must be able to effectively collaborate and remain organized to advance project goals for complex programs.

All applicants will be considered for both projects.

Knowledge and experience in a laboratory environment
Knowledge and experience in mammalian cell culture and molecular biology
Strong written and verbal communication skills
Excellent organizational and time management skills
The ability to adapt to new technologies and work efficiently across teams

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:
Legal authorization to work in the U.S.
At least 18 years of age prior to the scheduled start date
Be currently enrolled in an accredited college or university


Students majoring in Molecular Biology, Microbiology, Biochemistry, Biotechnology, or a related field.

Additional Information

All your information will be kept confidential according to EEO guidelines.

Keywords: Biogen, Cambridge , Co-op: Gene Therapy, Healthcare , Cambridge, Massachusetts

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