Senior Scientist - Immuno-Oncology Cell and Gene Therapy Group

Company: Novartis Group
Location: Cambridge
Posted on: January 16, 2022

Job Description:

Senior Scientist - Immuno-Oncology Cell and Gene Therapy Group Job Description 5600! That is the number of associates across the globe at the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.


We are seeking a highly motivated and skilled cell therapy scientist to join the Cell and Gene Therapy group within NIBR Exploratory Immuno-Oncology and contribute to developing pioneering CAR-T cell therapies. We are dedicated to discovering innovative cancer therapeutics and therapeutic formats that transform patients' lives and transform the field of cell therapy. You'll become a key individual contributor in a dynamic, multidisciplinary discovery team interrogating unique cell therapy platforms and will generate data that increases our understanding of emerging CAR-T cell therapies. The high-quality data generated will directly impact the development of future cell therapies and contribute to the design of future clinical trials aimed at improving outcomes for cancer patients. This position will be ideal for those candidates wishing to combine their interest in immuno-biology of cancer, with their strong desire to discover and help develop therapeutic approaches.

Key Responsibilities:
---Contribute to design of novel bioanalytical assays to improve the understanding of novel cell therapy products
---Conduct detailed in vitro characterization and testing of cell therapy products using protein and gene expression analysis
---Design and execute experiments independently; accurately record, analyze, and communicate data to senior staff and team members
---Work with internal and external partners to test, optimize and advance new cellular therapies into early development
---Present results in team meetings and deliver presentations to both small and large groups

EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. What you will bring to the role:

---BS/MS degree in biology-related or engineering subject area with 3-6 years of relevant biomedical research experience. Job title and grade level will be commensurate with experience and skillset.
---Knowledge of immunology, cellular therapies, and/or tumor immunology
---Understanding of ex-vivo cell-characterization by multi-color FACS and cytokine profiling (ELISA/MSD/Luminex), and gene expression analysis (qPCR, RNAseq)
---Prior experience with immune cell isolation techniques and the culture of primary human T cells
---Strong verbal and writing skills for documentation of data, drafting of technical reports, and communication of progress to manager and other team members.
---Ability to work in a fast-paced and team-oriented environment and adapt to changing directions/priorities.
---Demonstrated ability to quickly learn and perform in new areas, implement new techniques and instrumentation.
---Scientifically self-motivated, and capable of independently conducting, and critically analyzing own research with minimal supervision.

Desirable requirements:
---Experience with engineered T cell manufacturing and culture, including process optimization and functional testing of engineered T cells

Why consider Novartis?

769 million. That's how many lives our products touched in 2020. And while we're proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people's lives?
We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you're given opportunities to explore the power of digital and data. Where you're empowered to risk failure by taking smart risks, and where you're surrounded by people who share your determination to tackle the world's toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Novartis Group, Cambridge , Senior Scientist - Immuno-Oncology Cell and Gene Therapy Group, Healthcare , Cambridge, Massachusetts