Postdoctoral Associate - Cleary Lab
Company: Broad Institute
Location: Cambridge
Posted on: April 5, 2021
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Job Description:
We are seeking an experimental postdoctoral associate to join
the Cleary Lab at the Broad Institute in developing, testing and
deploying a new framework for experimental design based on recent
mathematical advances. This effort, led by Broad Fellow Dr. Brian
Cleary, will seek to manifest theoretical insights from applied
mathematics and computer science in new experimental modalities -
in particular the execution of random experiments and composite
experiments - to study tissue physiology, cellular pathways,
combinatorial interactions, and human genetics. We are looking for
a highly motivated individual to join our team in making
fundamental advances in experimental biology, and discoveries in
the organization and function of tissues, cellular pathways, and
the mechanisms of disease. This team will develop and apply
technologies combining microscopy and imaging transcriptomics,
CRISPR, single-cell measurements, proteomics, and microfluidic
automation. The Cleary Laboratory, established -1.5 years ago, is a
growing, interdisciplinary workplace at the interface of theory,
computation and experimentation, and is seeking to hire an
exceptional scientist who will work closely with both the Cleary
Lab and collaborators throughout the Broad community, MIT, and
Harvard. CHARACTERISTIC DUTIES Lead and collaborate with
scientists, postdoctoral and research associates to make
fundamental advances in experimental design Develop and apply
experimental strategies of random composite experiments to
functional omics techniques, including single-cell,
transcriptomics, proteomics, CRISPR-based assays in human cells and
tissues, and in situ omics Lead collaborations in the application
of new experimental designs to new biological systems and questions
Design and lead independent projects including developing methods,
techniques and evaluation criteria for obtaining results Make
significant contributions to scientific papers, quantitative data
analyses and presentations Contribute to generation of protocols
and data analyses Work with multidisciplinary team to achieve
project goals REQUIREMENTS Ph.D. in Molecular Biology,
Biochemistry, Genetics, Cell Biology, Systems Biology or related
field Strong hands-on experience in molecular biology, genomics,
and cellular biology (cell-based assays, primary and cell line
culture) Proven track record of critical scientific thinking,
multi-tasking ability, and strong analytical and problem-solving
skills Excellent interpersonal and collaborative skills, and the
ability to work both independently and as part of a team with
scientists from a wide range of research expertise The ideal
candidate will additionally have one or more of the following
qualifications: Experience with genome editing tools including
CRISPR targeting in various human cell types Experience with in
situ hybridization, immunostaining, and histopathological imaging
Experience with microscopy and microfluidic automation Experience
with culture and manipulation of primary cells Experience with
quantitative data analysis and proficiency in computational methods
and theory #LI-DNP All qualified applicants will receive
consideration for employment without regard to race, color,
religion, sex, sexual orientation, gender identity, national
origin, disability or protected veteran status. Check out this
video for a look into our community! Posted 30+ Days Ago Full time
3438 About Us The Broad Institute is pioneering a new model of
collaborative biomedical science to transform biology and medicine.
To do that, we have created a unique community of amazing, creative
people - "Broadies" - each with a passion for pushing scientific
frontiers. Broadies have a diverse collection of talents,
expertise, and backgrounds, creating a rich collaborative
environment for solving intractable scientific problems. We are
always looking for new team members within Research , Computational
Biology , Software Engineering , and Administration to help us
tackle important problems at the cutting edge of science. Why
Broad? It comes down to our culture . Our community transcends
academic and organizational barriers, encouraging different points
of view and making all Broadies part of something meaningful. If
ours is a community you would want to be a part of, then please
apply!
Keywords: Broad Institute, Cambridge , Postdoctoral Associate - Cleary Lab, Healthcare , Cambridge, Massachusetts
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