Senior Research Associate, Non Clinical

Company: Ultragenyx Pharmaceutical
Location: Cambridge
Posted on: February 24, 2021

Job Description:

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do.--To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won't go - challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.-- Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth - so employees can thrive in all areas of their lives, in and outside of work. -- Ultimately, we want to be an organization where we would be proud for our family, friends and children to work. If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and -- personally, come join our team.-- During the COVID-19 Outbreak,--we are committed to our hiring process. The health and safety of our employees and prospective employees take priority which means at this time our--approach--will include--video discussions, interviews, and--onboarding. Position Summary ultraimpact - Make a difference for those who need it most This individual will support advancement of innovative AAV-based therapeutics by performing a variety of cell-based and molecular techniques. The candidate will also be responsible for mammalian cell culture and assist in the development and execution of in vitro assays. Responsibilities

• Work on a dynamic team to assess AAV gene therapy vectors in vitro
• Perform mammalian cell culture experiments with a variety of immortalized cell lines
• Design, conduct and optimize in vitro experiments utilizing standard molecular biology techniques
• Assist in development and implementation of novel cell-based assays
• Work on a dynamic and cross functional team to assess AAV gene therapy vectors in vitro
• Communicate results and research progress during team and departmental meetings
• Prepare, write, analyze, and present data and reports
• Expand upon scientific knowledge and contribute innovative ideas to product development Requirements
  • BS or MS in biology, molecular biology, biochemistry, or related discipline with 2-6 years of experience in academic or industry setting; knowledge of muscle biology a plus
  • Expertise in mammalian cell culture, including cell line maintenance; experience with plasmid transfections and viral transductions a plus
  • Solid knowledge of molecular biology techniques (e.g. qPCR, Western Blot, ELISA, enzymatic assays, DNA/RNA/protein extraction); immunofluorescence experience a plus
  • Familiarity with microscopy, fluorescent and brightfield a plus
  • Familiarity with data and image analysis software (e.g. GraphPad Prism, ImageJ)
  • Desire to work in a fast-paced, start-up environment, innovate and independently drive projects forward
  • Ability to simultaneously support multiple programs and ensure meeting of timelines
  • Strong collaboration, team-working skills and communication skills
  • Self-motivated and detail-oriented with good problem-solving ability Ultragenyx Pharmaceutical is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status. Reasonable accommodation will be provided for qualified individuals with disabilities and for qualified disabled veterans in job application procedures, as required by applicable law. If you have any difficulty using our online application system and need an accommodation due to a disability, you may contact--Talent Acquisition--by calling:--(415) 483-8800--or by--emailing--us at--talentacquisition@ultragenyx.com . For electronic email and mail inquiries, please include a description of your requested accommodation, your name and contact information. Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to:--talentacquisition@ultragenyx.com .

Keywords: Ultragenyx Pharmaceutical, Cambridge , Senior Research Associate, Non Clinical, Healthcare , Cambridge, Massachusetts